The Imaging and Physics group’s research focus is the field of medical imaging, specifically molecular- (Positron Emission Tomography – PET, Single Photon Emission Computed Tomography – SPECT) and multimodal imaging (PET/CT, SPECT/CT, PET/MRI).
Research projects
Testing new instrumentation for SPECT
Optimizing PET and SPECT imaging using patient-individual 3-D printed phantoms
Identifying clinical applications of quantitative SPECT/CT
Developing methods for 3-D dosimetry in therapeutic Nuclear Medicine
Recent publications
2022
Grings, A., Jobic, C., Kuwert, T., & Ritt, P. (2022). The magnitude of the partial volume effect in SPECT imaging of the kidneys: a phantom study . EJNMMI Physics , 9 (1). https://doi.org/10.1186/s40658-022-00446-2
Kugler, A., Kuwert, T., Ritt, P., & Grings, A. (2022). Influence of CT metal artifact reduction on SPECT/CT quantification of bone scintigraphy - Retrospective study for selected types of metal implants . Nuklearmedizin-Nuclear Medicine . https://doi.org/10.1055/a-1883-9281
Ritt, P. (2022). Recent Developments in SPECT/CT . Seminars in Nuclear Medicine . https://doi.org/10.1053/j.semnuclmed.2022.01.004
2021
Beck, M., Rugel, G., Reinfelder, J., Kuwert, T., Ritt, P., Kreißel, S., & Schlittenbauer, T. (2021). Quantitative Analysis of Multimodal Skeletal SPECT/CT Reconstructions in Diagnosing Medication-related Osteonecrosis of the Jaw . Nuklearmedizin-Nuclear Medicine . https://doi.org/10.1055/a-1525-7621
Bergmann, C., Distler, J., Treutlein, C., Tascilar, K., Müller, A., Atzinger, A.,... Schmidkonz, C. (2021). 68GA-FAPI-04 PET/CT STUDY EXTENSION FOR THE ASSESSMENT OF FIBROBLAST ACTIVATION AND RISK EVALUATION IN SYSTEMIC SCLEROSIS-RELATED INTERSTITIAL LUNG DISEASE . In ANNALS OF THE RHEUMATIC DISEASES (pp. 165-166). LONDON: BMJ PUBLISHING GROUP.
Bergmann, C., Distler, J., Treutlein, C., Tascilar, K., Müller, A., Atzinger, A.,... Schmidkonz, C. (2021). 68Ga-FAPI-04 PET-CT for molecular assessment of fibroblast activation and risk evaluation in systemic sclerosis-associated interstitial lung disease: a single-centre, pilot study . The Lancet Rheumatology . https://doi.org/10.1016/S2665-9913(20)30421-5
Grings, A., Kuwert, T., & Ritt, P. (2021). Determination of Partial-Volume Effect in Patient-Individual Kidney Phantoms for Tc-99m SPECT/CT . In EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (pp. S481-S482). NEW YORK: SPRINGER.
Grings, A., Reymann, M., Vija, A.H., Kuwert, T., & Ritt, P. (2021). Patient-Specific Phantoms for Tc-99m Brain Perfusion Imaging with SPECT/CT . In EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (pp. S482-S483). NEW YORK: SPRINGER.
Khushu, S., Von Gall, C.C.A., Reymann, M., Sibille, L., Spottiswoode, B., Ritt, P.,... Shah, V. (2021). Whole body non-rigid PET/CT alignment using synthetic CT generation from non-attenuation corrected F-18-FDG PET images with a 3D CycleGAN . In EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (pp. S326-S326). NEW YORK: SPRINGER.
Ritt, P., Heim, P., Grings, A., Beck, M., & Kuwert, T. (2021). Normal Values of Skeletal Tc-99m-labelled Bisphosphonate Uptake in SPECT/CT . In EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (pp. S589-S590). NEW YORK: SPRINGER.
Ritt, P., Jobic, C., Beck, M., Schmidkonz, C., Kuwert, T., Uder, M., & Brand, M. (2021). Dissimilar DNA Damage to Blood Lymphocytes After 177Lu-Labeled DOTATOC or Prostate-Specific Membrane Antigen Therapy . Journal of Nuclear Medicine , 62 (3), 379-385. https://doi.org/10.2967/jnumed.120.243782
Ritt, P., Jobic, C., Grings, A., Beck, M., Schmidkonz, C., Kuwert, T.,... Brand, M. (2021). Potential Limitations of Established Blood-Dosimetry Models for Lu-177 Therapy . In EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (pp. S394-S394). NEW YORK: SPRINGER.
Schmidkonz, C., Distler, J., Treutlein, C., Atzinger, A., Prante, O., Ritt, P.,... Bergmann, C. (2021). Ga-68-FAPI-04 PET/CT for molecular assessment of fibroblast activation and risk evaluation in systemic sclerosis-related interstitial lung disease . European Journal of Nuclear Medicine and Molecular Imaging , S158-S159. https://doi.org/10.1055/s-0041-1726695
Schmidkonz, C., Rauber, S., Atzinger, A., Götz, T.I., Soare, A., Cordes, M.,... Ramming, A. (2021). Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging . European Journal of Nuclear Medicine and Molecular Imaging , S125-S126. https://doi.org/10.1055/s-0041-1726701
2020
Goetz, T.I., Lang, E.W., Prante, O., Maier, A., Cordes, M., Kuwert, T.,... Schmidkonz, C. (2020). Three-dimensional Monte Carlo-based voxel-wise tumor dosimetry in patients with neuroendocrine tumors who underwent 177Lu-DOTATOC therapy . Annals of Nuclear Medicine . https://doi.org/10.1007/s12149-020-01440-3
Götz, T.I., Lang, E.W., Prante, O., Cordes, M., Kuwert, T., Ritt, P.,... Schmidkonz, C. (2020). Estimation of [177Lu]PSMA-617 tumor uptake based on voxel-wise 3D Monte Carlo tumor dosimetry in patients with metastasized castration resistant prostate cancer . Nuklearmedizin-Nuclear Medicine . https://doi.org/10.1055/a-1204-9932
Mürschberger, N., Reymann, M., Cachovan, M., Ritt, P., Vija, H., & Maier, A. (2020, November). U-Net for Multi-Organ Segmentation of SPECT Projection Data . Poster presentation at IEEE, Boston, Massachuchets, US.
Reymann, M., Massanes, F., Ritt, P., Cachovan, M., Kuwert, T., Vija, A.H., & Maier, A. (2020, November). Feature Loss After Denoising of SPECT Projection Data using a U-Net . Poster presentation at 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference, Boston, Massachusetts, US.
Ritt, P., & Kuwert, T. (2020). Quantitative SPECT/CT-Technique and Clinical Applications . Recent Results in Cancer Research , 216 , 565-590. https://doi.org/10.1007/978-3-030-42618-7_17
Ritt, P., Seidl, K., Cachovan, M., Vija, A., & Kuwert, T. (2020). Data-Driven Respiratory SPECT-Gating for Pre-Radio-Embolization Determination of Liver-Lung-Shunt Fraction . In JOURNAL OF NUCLEAR MEDICINE . RESTON: SOC NUCLEAR MEDICINE INC.
Roschlein, M., Gotz, T., Schmidkonz, C., Beck, M., Kuwert, T., & Ritt, P. (2020). Effect of Reconstruction Settings on PET-Derived Dose-Volume-Histograms after SIRT of the Liver . In JOURNAL OF NUCLEAR MEDICINE . RESTON: SOC NUCLEAR MEDICINE INC.
Schmidkonz, C., Atzinger, A., Götz, T., Beck, M., Ritt, P., Prante, O.,... Cordes, M. (2020). 99mTc-MIP-1404 SPECT/CT for Patients With Metastatic Prostate Cancer: Interobserver and Intraobserver Variability in Treatment-Related Longitudinal Tracer Uptake Assessments of Prostate-Specific Membrane Antigen-Positive Lesions . Clinical Nuclear Medicine , 45 (2), 105-112. https://doi.org/10.1097/RLU.0000000000002880
Schmidkonz, C., Götz, T.I., Atzinger, A., Ritt, P., Prante, O., Kuwert, T.,... Cordes, M. (2020). 99mTc-MIP-1404 SPECT/CT for Assessment of Whole-Body Tumor Burden and Treatment Response in Patients With Biochemical Recurrence of Prostate Cancer . Clinical Nuclear Medicine . https://doi.org/10.1097/RLU.0000000000003102
Schmidkonz, C., Krumbholz, M., Atzinger, A., Cordes, M., Götz, T., Prante, O.,... Metzler, M. (2020). Correction to: Assessment of treatment responses in children and adolescents with Ewing sarcoma with metabolic tumor parameters derived from 18F-FDG-PET/CT and circulating tumor DNA (European Journal of Nuclear Medicine and Molecular Imaging, (2019), 10.1007/s00259-019-04649-1) . European Journal of Nuclear Medicine and Molecular Imaging . https://doi.org/10.1007/s00259-019-04672-2
Schmidkonz, C., Rauber, S., Atzinger, A., Agarwal, R., Götz, T.I., Soare, A.,... Ramming, A. (2020). Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging . Annals of the Rheumatic Diseases , 79 (11), 1485-1491. https://doi.org/10.1136/annrheumdis-2020-217408
Schmidt, M., Engelhorn, T., Lang, S., Lücking, H., Hölter, P., Fröhlich, K.,... Dörfler, A. (2020). DSC Brain Perfusion Using Advanced Deconvolution Models in the Diagnostic Work-Up of Dementia and Mild Cognitive Impairment: A Semiquantitative Comparison with HMPAO-SPECT-Brain Perfusion . Journal of Clinical Medicine , 9 (6). https://doi.org/10.3390/jcm9061800
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The Imaging and Physics group’s research focus is the field of medical imaging, specifically molecular- (Positron Emission Tomography – PET, Single Photon Emission Computed Tomography – SPECT) and multimodal imaging (PET/CT, SPECT/CT, PET/MRI).
Research projects
No projects found.
2022
2021
2020
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