Our research (Medical Physics Group in the Erlangen Centre for Astroparticle Physics) is focused on measurements and detection of ionising radiation in medicine. Project examples are: development of spectroscopic x-ray pixel detectors in collaboration with CERN, development of an eye lens x-ray dosimeter for interventional radiography, radiation monitoring in FLASH radiation therapy, gamma dosimetry in collaboration with Physikalisch Technische Bundesanstalt, interferometric x-ray imaging.
Research projects
Development of spectroscopic x-ray pixel detectors in collaboration with CERN: Since many years, ECAP is member of the internaional Medipix collaborations with seat at CERN. There we develop ultra-fast, high-granularity photon-counting, spectroscopic pixel detectors for ionising radiation imaging and dose measurements. ECAP contributes with medical applications to the development of new detectors.
Development of an eye lens x-ray dosimeter for interventional radiography: Here, we develop a small wearable electronics dosimeter to be used by radiologists in interventional radiography based on our own pixel detector Dosepix that has been developed in a collaboration between ECAP and CERN.
Radiation monitoring in FLASH radiation therapy: Within the international UHD-pulse consortium, we will investigate the use of pixel detectors, e.g. the Dosepix, for flux monitoring/for beam control in ultra-high dose rate radiation therapy (FLASH).
Gamma dosimetry in collaboration with Physikalisch Technische Bundesanstalt: Together with PTB in Braunschweig, we investigate the use of photon counting pixel detectors for measurements of equivalent doses in pulsed radiation fields and for high-flux spectroscopy.
Interferometric x-ray imaging: Here, we use and develop Talbot-Lau x-ray interferometers (3 microstructured gratings in the beam path) to measure images of the phase shift of x-ray waves through the object and to measure the granularity of the object on the micrometer scale.
Recent publications
2024
Schreiner, S., Rauch, C., Akstaller, B., Bleuel, P., Fröjdh, E., Ludwig, V.,... Funk, S. (2024). Design of a Talbot phase-contrast microscopy imaging system with a digital detector for laser-driven X-ray backlighter sources . Journal of Instrumentation , 19 (5). https://doi.org/10.1088/1748-0221/19/05/P05004
Wegert, L., Schreiner, S., Rauch, C., Albertazzi, B., Bleuel, P., Fröjdh, E.,... Funk, S. (2024). Demonstrating grating-based phase-contrast imaging of laser-driven shock waves . Matter and Radiation at Extremes , 9 (4). https://doi.org/10.1063/5.0200440
2023
Beiser, F., Haag, D., Ballabriga, R., Behrens, R., Campbell, M., Fuhg, C.,... Michel, T. (2023). Active Personal Eye Lens Dosimetry with the Hybrid Pixelated Dosepix Detector . IEEE Transactions on Radiation and Plasma Medical Sciences , 1-1. https://doi.org/10.1109/TRPMS.2023.3301503
Kumar, K., Fachet, M., Al-Maatoq, M., Chakraborty, A., Khismatrao, R.S., Oka, S.V.,... Hoeschen, C. (2023). Characterization of a polychromatic microfocus X-ray fluorescence imaging setup with metallic contrast agents in a microphysiological tumor model . Frontiers in Physics , 11 . https://doi.org/10.3389/fphy.2023.1125143
Schreiner, S., Rauch, C., Akstaller, B., Bleuel, P., Frojdh, E., Martynenko, A.S.,... Funk, S. (2023). Erratum: Publisher's Note: "Electromagnetic pulse protective shielding for digital x-ray detectors" [Rev. Sci. Instrum. 94, 075106 (2023) (The Review of scientific instruments (2023) 94 7 PII: 089902) . Review of Scientific Instruments , 94 (8). https://doi.org/10.1063/5.0170081
Schreiner, S., Rauch, C., Akstaller, B., Bleuel, P., Fröjdh, E., Martynenko, A.S.,... Funk, S. (2023). Electromagnetic pulse protective shielding for digital x-ray detectors . Review of Scientific Instruments , 94 (7). https://doi.org/10.1063/5.0160120
2022
Ackerman, N., Albert, J., Auger, M., Auty, D.J., Badhrees, I., Barbeau, P.S.,... Ziegler, T. (2022). The EXO-200 detector, part II: Auxiliary systems . Journal of Instrumentation , 17 (2). https://doi.org/10.1088/1748-0221/17/02/P02015
Akstaller, B., Schreiner, S., Dietrich, L., Rauch, C., Schuster, M., Ludwig, V.,... Funk, S. (2022). X-ray Dark-Field Imaging for Improved Contrast in Historical Handwritten Literature . Journal of Imaging , 8 (9). https://doi.org/10.3390/jimaging8090226
Behrens, R., Hufschmidt, P., Roth, J., Akstaller, B., Hupe, O., Haag, D.,... Michel, T. (2022). Radiation measurements and simulations at the PHELIX laser facility, GSI . Journal of Instrumentation , 17 (5). https://doi.org/10.1088/1748-0221/17/05/P05033
Karl, S., Zmija, A., Richter, S., Vogel, N., Malyshev, D., Zink, A.,... Funk, S. (2022). Comparing different approaches for stellar intensity interferometry . Monthly Notices of the Royal Astronomical Society , 512 (2), 1722-1729. https://doi.org/10.1093/mnras/stac489
Wolf, A., Akstaller, B., Cipiccia, S., Flenner, S., Hagemann, J., Ludwig, V.,... Funk, S. (2022). Single-exposure X-ray phase imaging microscopy with a grating interferometer . Journal of Synchrotron Radiation , 29 , 794-806. https://doi.org/10.1107/S160057752200193X
Zmija, A., Vogel, N., Anton, G., Malyshev, D., Michel, T., Zink, A., & Funk, S. (2022). Optical intensity interferometry lab tests in preparation of stellar diameter measurements at IACTs at GHz photon rates . Monthly Notices of the Royal Astronomical Society , 509 (3), 3113-3118. https://doi.org/10.1093/mnras/stab3058
2021
Akstaller, B., Schreiner, S., Hofmann, F., Meyer, P., Neumayer, P., Schuster, M.,... Funk, S. (2021). Single-shot grating-based phase-contrast imaging of a micrometer sample at a laser-driven x-ray backlighter source . Journal of Instrumentation , 16 (6). https://doi.org/10.1088/1748-0221/16/06/P06021
Haag, D., Schmidt, S., Hufschmidt, P., Eberle, F., Michel, T., Anton, G.,... Wong, W. (2021). Personal Dosimetry in Continuous Photon Radiation Fields with the Dosepix Detector . IEEE Transactions on Nuclear Science . https://doi.org/10.1109/TNS.2021.3068832
Schreiner, S., Akstaller, B., Dietrich, L., Meyer, P., Neumayer, P., Schuster, M.,... Funk, S. (2021). Noise reduction for single-shot grating-based phase-contrast imaging at an x-ray backlighter . Journal of Imaging , 7 (9). https://doi.org/10.3390/jimaging7090178
Stiegler, T., Sangiorgio, S., Brodsky, J.P., Heffner, M., Kharusi, S.A., Anton, G.,... Ziegler, T. (2021). Event reconstruction in a liquid xenon Time Projection Chamber with an optically-open field cage . Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment , 1000 . https://doi.org/10.1016/j.nima.2021.165239
2020
Al Kharusi, S., Anton, G., Badhrees, I., Barbeau, P.S., Beck, D., Belov, V.,... Ziegler, T. (2020). Measurement of the Spectral Shape of the beta-Decay of Xe-137 to the Ground State of Cs-137 in EXO-200 and Comparison with Theory . Physical Review Letters , 124 (23). https://doi.org/10.1103/PhysRevLett.124.232502
Anton, G., Badhrees, I., Barbeau, P.S., Beck, D., Belov, V., Bhatta, T.,... Ziegler, T. (2020). Measurement of the scintillation and ionization response of liquid xenon at MeV energies in the EXO-200 experiment . Physical Review C - Nuclear Physics , 101 (6). https://doi.org/10.1103/PhysRevC.101.065501
Emons, J., Fasching, P., Wunderle, M., Heindl, F., Rieger, J., Horn, F.,... Jud, S. (2020). Assessment of the additional clinical potential of X-ray dark-field imaging for breast cancer in a preclinical setup . Therapeutic Advances in Medical Oncology , 12 . https://doi.org/10.1177/1758835920957932
Emons, J., Fasching, P., Wunderle, M., Heindl, F., Rieger, J., Horn, F.,... Jud, S.M. (2020). Assessment of the additional clinical potential of X-ray dark-field imaging for breast cancer in a preclinical setup . In GEBURTSHILFE UND FRAUENHEILKUNDE (pp. E111-E111). STUTTGART: GEORG THIEME VERLAG KG.
Ludwig, V., Akstaller, B., Schuster, M., Seifert, M., Wolf, A., Michel, T., & Anton, G. (2020). A phase-sampling method for an X-ray Talbot-Lau scanner with continuous grating movement . Journal of Instrumentation , 15 (1). https://doi.org/10.1088/1748-0221/15/01/P01010
Lv, P., Cao, G.F., Wen, L.J., Kharusi, S.A., Anton, G., Arnquist, I.J.,... Ziegler, T. (2020). Reflectance of Silicon Photomultipliers at Vacuum Ultraviolet Wavelengths . IEEE Transactions on Nuclear Science , 67 (12), 2501-2510. https://doi.org/10.1109/TNS.2020.3035172
Nakarmi, P., Ostrovskiy, I., Soma, A.K., Retière, F., Kharusi, S.A., Alfaris, M.,... Ziegler, T. (2020). Reflectivity and PDE of VUV4 Hamamatsu SiPMs in liquid xenon . Journal of Instrumentation , 15 (1). https://doi.org/10.1088/1748-0221/15/01/P01019
Njoya, O., Tsang, T., Tarka, M., Fairbank, W., Kumar, K.S., Rao, T.,... Ziegler, T. (2020). Measurements of electron transport in liquid and gas Xenon using a laser-driven photocathode . Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment , 972 . https://doi.org/10.1016/j.nima.2020.163965
Rauch, T., Rieger, J., Pelzer, G., Horn, F., Erber, R., Wunderle, M.,... Anton, G. (2020). Discrimination analysis of breast calcifications using x-ray dark-field radiography . Medical Physics . https://doi.org/10.1002/mp.14043
Seifert, M., Weule, M., Cipiccia, S., Flenner, S., Hagemann, J., Ludwig, V.,... Akstaller, B. (2020). Evaluation of the Weighted Mean X-ray Energy for an Imaging System Via Propagation-Based Phase-Contrast Imaging . Journal of Imaging , 6 (7). https://doi.org/10.3390/jimaging6070063
Zmija, A., Deiml, P., Malyshev, D., Zink, A., Anton, G., Michel, T., & Funk, S. (2020). LED as laboratory test source for astronomical intensity interferometry . Optics Express , 28 (4), 5248-5256. https://doi.org/10.1364/OE.28.005248
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Contact:
Our research (Medical Physics Group in the Erlangen Centre for Astroparticle Physics) is focused on measurements and detection of ionising radiation in medicine. Project examples are: development of spectroscopic x-ray pixel detectors in collaboration with CERN, development of an eye lens x-ray dosimeter for interventional radiography, radiation monitoring in FLASH radiation therapy, gamma dosimetry in collaboration with Physikalisch Technische Bundesanstalt, interferometric x-ray imaging.
Research projects
No projects found.
2024
2023
2022
2021
2020
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