My research is focussed on the development of efficient image acquisition, image reconstruction and post-processing techniques for ultra-high field and multi-nuclear magnetic resonance imaging. The aim is to develop and to evaluate these techniques for inter-disciplinary clinical research.
Research projects
Ultra-high field MRI
Multi-nuclear MRI
Parallel transmission (pTx) application of advanced MRI techniques in clinical research
Recent publications
2024
Bäuchle, T.A., Stuprich, C., Loh, M., Nagel, A.M., Uder, M., & Laun, F.B. (2024). Influence of Magnetic Field Strength on Intravoxel Incoherent Motion Parameters in Diffusion MRI of the Calf . Tomography , 10 (5), 773-788. https://doi.org/10.3390/tomography10050059
Egger, N., Nagelstraßer, S., Wildenberg, S., Bitz, A., Ruck, L., Herrler, J.,... Nagel, A.M. (2024). Accelerated B+1 mapping and robust parallel transmit pulse design for heart and prostate imaging at 7 T . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.30185
Eisen, C., Liebig, P., Herrler, J., Ritter, D., Lévy, S., Uder, M.,... Grodzki, D. (2024). Fast online spectral-spatial pulse design for subject-specific fat saturation in cervical spine and foot imaging at 1.5 T. Magnetic Resonance Materials in Physics Biology and Medicine , 37 (2), 257-272. https://doi.org/10.1007/s10334-024-01149-8
Gerhalter, T., Schilling, F., Zeitouni, N., Linz, P., Baudin, P.Y., Kannenkeril, D.,... Gast, L. (2024). Sodium quantification in skeletal muscle: comparison between Cartesian gradient-echo and radial ultra-short echo time 23Na MRI techniques . European Radiology Experimental , 8 (1). https://doi.org/10.1186/s41747-024-00461-1
Heiß, R., Höger, S., Uder, M., Hotfiel, T., Hanspach, J., Laun, F.B.,... Roemer, F. (2024). Early functional and morphological changes of calf muscles in delayed onset muscle soreness (DOMS) assessed with 7T MRI . Annals of Anatomy-Anatomischer Anzeiger , 251 . https://doi.org/10.1016/j.aanat.2023.152181
Heiß, R., Weber, M.A., Balbach, E., Hinsen, M., Geißler, F., Nagel, A.M.,... Roemer, F. (2024). Correction to: Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI (European Radiology Experimental, (2023), 7, 1, (80), 10.1186/s41747-023-00394-1) . European Radiology Experimental , 8 (1). https://doi.org/10.1186/s41747-024-00449-x
Hinsen, M., Heiß, R., Nagel, A.M., Levy, S., Uder, M., Bickelhaupt, S., & May, M. (2024). Lungenbildgebung in der Niederfeld-Magnetresonanztomographie . Zeitschrift für Pneumologie , 21 , 29-37. https://doi.org/10.1007/s10405-024-00543-2
Kamp, B., Radke, K.L., Knet, M., Strunk, R., Gallinnis, P.J., Nagel, A.M.,... Müller-Lutz, A. (2024). Sodium MRI of the Lumbar Intervertebral Discs of the Human Spine: An Ex Vivo Study . Journal of Magnetic Resonance Imaging . https://doi.org/10.1002/jmri.29521
Kilic, T., Liebig, P., Demirel, O.B., Herrler, J., Nagel, A.M., Ugurbil, K., & Akçakaya, M. (2024). Unsupervised deep learning with convolutional neural networks for static parallel transmit design: A retrospective study . Magnetic Resonance in Medicine , 91 (6), 2498-2507. https://doi.org/10.1002/mrm.30014
Kircher, K., Chaudry, O., Nagel, A.M., Ghasemikaram, M., Uder, M., Jakob, F.,... Engelke, K. (2024). Effects of high-intensity training on fatty infiltration in paraspinal muscles in elderly males with osteosarcopenia – the randomized controlled FrOST study . BMC Geriatrics , 24 (1). https://doi.org/10.1186/s12877-024-04736-5
Kopp, C., Kittler, L., Linz, P., Kannenkeril, D., Horn, S., Chazot, C.,... Dahlmann, A. (2024). Modification of Dialysate Na+ Concentration but not Ultrafiltration or Dialysis Treatment Time Affects Tissue Na+ Deposition in Patients on Hemodialysis. Kidney International Reports , 9 (5), 1310-1320. https://doi.org/10.1016/j.ekir.2024.02.002
Kopp, M., Wiesmüller, M., Buchbender, M., Kesting, M.R., Nagel, A.M., May, M.,... Heiß, R. (2024). MRI of Temporomandibular Joint Disorders: A Comparative Study of 0.55 T and 1.5 T MRI. Investigative Radiology , 59 (3), 223-229. https://doi.org/10.1097/RLI.0000000000001008
Marton, A., Saffari, S.E., Rauh, M., Sun, R.N., Nagel, A.M., Linz, P.,... Titze, J. (2024). Water Conservation Overrides Osmotic Diuresis During SGLT2 Inhibition in Patients With Heart Failure . Journal of the American College of Cardiology , 83 (15), 1386-1398. https://doi.org/10.1016/j.jacc.2024.02.020
Pachowsky, M., Söllner, S., Gelse, K., Sambale, J., Nagel, A.M., Schett, G.,... Heiß, R. (2024). Primary anterior cruciate ligament repair-morphological and quantitative assessment by 7-T MRI and clinical outcome after 1.5 years. European Radiology , 34 (8), 5007-5015. https://doi.org/10.1007/s00330-024-10603-z
Pogarell, T., Heiß, R., Janka, R.M., Nagel, A.M., Uder, M., & Roemer, F. (2024). Modern low-field MRI . Skeletal Radiology . https://doi.org/10.1007/s00256-024-04597-4
Stuprich, C., Loh, M., Nemerth, J., Nagel, A.M., Uder, M., & Laun, F.B. (2024). Velocity-compensated intravoxel incoherent motion of the human calf muscle . Magnetic Resonance in Medicine , 92 (2), 543-555. https://doi.org/10.1002/mrm.30059
Tkotz, K., Liebert, A., Gast, L., Zeiger, P., Uder, M., Zaiß, M., & Nagel, A.M. (2024). Multi-echo–based fat artifact correction for CEST MRI at 7 T . Magnetic Resonance in Medicine , 91 (2), 481-496. https://doi.org/10.1002/mrm.29863
Tkotz, K., Zeiger, P., Hanspach, J., Mathy, C., Laun, F.B., Uder, M.,... Gast, L. (2024). Parameter optimization for proton density fat fraction quantification in skeletal muscle tissue at 7 T . Magnetic Resonance Materials in Physics Biology and Medicine . https://doi.org/10.1007/s10334-024-01195-2
Zeng, R., Schlaeger, S., Türk, M., Baum, T., Deschauer, M., Janka, R.M.,... Schmidt, J. (2024). Expertenempfehlung zur Magnetresonanztomographie bei Muskelerkrankungen . Der Nervenarzt . https://doi.org/10.1007/s00115-024-01673-x
Zeng, R., Schlaeger, S., Türk, M., Baum, T., Deschauer, M., Janka, R.M.,... Schmidt, J. (2024). [Expert recommendations for magnetic resonance imaging of muscle disorders]. Die Radiologie , 64 (8), 653-662. https://doi.org/10.1007/s00117-024-01276-2
2023
Bayer, T., Brockhoff, M.-J., Nagel, A.M., Adler, W., Lutter, C., Janka, R.M.,... Roemer, F. (2023). Evaluation of finger cartilage composition in recreational climbers with 7 Tesla T2 mapping magnetic resonance imaging . Frontiers in Sports and Active Living , 5 . https://doi.org/10.3389/fspor.2023.1248581
Engelke, K., Chaudry, O., Gast, L., Eldib, M.A., Wang, L., Laredo, J.D.,... Nagel, A.M. (2023). Magnetic resonance imaging techniques for the quantitative analysis of skeletal muscle: State of the art. Journal of Orthopaedic Translation , 42 , 57-72. https://doi.org/10.1016/j.jot.2023.07.005
Gast, L., Baier, L.M., Meixner, C., Chaudry, O., Engelke, K., Uder, M.,... Heiß, R. (2023). MRI of Potassium and Sodium Enables Comprehensive Analysis of Ion Perturbations in Skeletal Muscle Tissue After Eccentric Exercise. Investigative Radiology , 58 (4), 265-272. https://doi.org/10.1097/RLI.0000000000000931
Gast, L., Platt, T., Nagel, A.M., & Gerhalter, T. (2023). Recent technical developments and clinical research applications of sodium (23Na) MRI . Progress in Nuclear Magnetic Resonance Spectroscopy , 138-139 , 1-51. https://doi.org/10.1016/j.pnmrs.2023.04.002
Heiß, R., Janka, R.M., Uder, M., Hotfiel, T., Gast, L., Nagel, A.M., & Roemer, F. (2023). Imaging of muscle injuries in sports medicine . Die Radiologie . https://doi.org/10.1007/s00117-023-01118-7
Heiß, R., Weber, M.A., Balbach, E., Hinsen, M., Geißler, F., Nagel, A.M.,... Roemer, F. (2023). Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI . European Radiology Experimental , 7 (1). https://doi.org/10.1186/s41747-023-00394-1
Heiß, R., Weber, M.-A., Balbach, E., Schmitt, R., Rehnitz, C., Laqmani, A.,... Roemer, F. (2023). Clinical Application of Ultrahigh-Field-Strength Wrist MRI: A Multireader 3-T and 7-T Comparison Study . Radiology , 307 (2), e220753-. https://doi.org/10.1148/radiol.220753
Herrler, J., Williams, S.N., Liebig, P., Ding, B., McElhinney, P., Allwood-Spiers, S.,... Maier, A. (2023). The effects of RF coils and SAR supervision strategies for clinically applicable nonselective parallel-transmit pulses at 7 T . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.29569
Kapsner, L., Balbach, E., Folle, L., Laun, F.B., Nagel, A.M., Liebert, A.,... Bickelhaupt, S. (2023). Image quality assessment using deep learning in high b-value diffusion-weighted breast MRI. Scientific Reports , 13 (1). https://doi.org/10.1038/s41598-023-37342-3
Kreitz, S., Mennecke, A., Konerth, L., Rösch, J., Nagel, A.M., Laun, F.B.,... Heß, A. (2023). 3T vs. 7T fMRI: capturing early human memory consolidation after motor task utilizing the observed higher functional specificity of 7T . Frontiers in Neuroscience , 17 . https://doi.org/10.3389/fnins.2023.1215400
Kreitz, S., Mennecke, A., Konerth, L., Rösch, J., Nagel, A.M., Laun, F.B.,... Heß, A. (2023). 3T vs. 7T fMRI: capturing early human memory consolidation after motor task utilizing the observed higher functional specificity of 7T . Frontiers in Neuroscience , 17 . https://doi.org/10.3389/fnins.2023.1215400
Wiesmüller, M., Kopp, M., Sievert, M., May, M., Nagel, A.M., Iro, H.,... Heiß, R. (2023). Comparison of vestibular schwannoma visualization between 0.55 T and 1.5 T MRI . European Journal of Radiology , 165 . https://doi.org/10.1016/j.ejrad.2023.110927
Zbýň, Š., Ludwig, K.D., Watkins, L.E., Lagore, R.L., Nowacki, A., Tóth, F.,... Ellermann, J.M. (2023). Changes in tissue sodium concentration and sodium relaxation times during the maturation of human knee cartilage: Ex vivo 23Na MRI study at 10.5 T . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.29930
2022
Engelke, K., Chaudry, O., Ghasemikaram, M., Nagel, A.M., Jakob, F., & Kemmler, W. (2022). Age Related Increase of Intermuscular Adipose Tissue of the Thigh can be Prevented by Exercise in Sarcopenic Men . In JOURNAL OF BONE AND MINERAL RESEARCH (pp. 174-174). HOBOKEN: WILEY.
Engelke, K., Ghasemikaram, M., Chaudry, O., Uder, M., Nagel, A.M., Jakob, F., & Kemmler, W. (2022). The effect of ageing on fat infiltration of thigh and paraspinal muscles in men . Aging Clinical and Experimental Research . https://doi.org/10.1007/s40520-022-02149-1
Engelke, K., Ghasemikaram, M., Chaurdy, O., Uder, M., Nagel, A.M., Jacob, F., & Kemmler, W. (2022). EFFECT OF AGEING ON FAT INFILTRATION OF THIGH AND PARASPINAL MUSCLES IN MEN . In AGING CLINICAL AND EXPERIMENTAL RESEARCH (pp. S356-S357). NEW YORK: SPRINGER.
Folle, L., Tkotz, K., Gadjimuradov, F., Kapsner, L., Fabian, M., Bickelhaupt, S.,... Maier, A. (2022). Towards Super-resolution CEST MRI for Visualization of Small Structures . In Klaus Maier-Hein, Thomas M. Deserno, Heinz Handels, Andreas Maier, Christoph Palm, ThomasTolxdorff (Eds.), Bildverarbeitung für die Medizin 2022. (pp. 210-215). Wiesbaden: Springer Vieweg.
Folle, L., Tkotz, K., Liebert, A., Gadjimuradov, F., Kapsner, L., Fabian, M.,... Maier, A. (2022). Super-Resolution for CEST MRI .
Friedrich, A.C., Linz, P., Nagel, A.M., Rosenhauer, D., Horn, S., Schiffer, M.,... Dahlmann, A. (2022). Hemodialysis Patients with Cardiovascular Disease Reveal Increased Tissue Na+ Deposition . Kidney & Blood Pressure Research , 47 (3), 185-193. https://doi.org/10.1159/000520821
Gast, L., Baier, L.-M., Chaudry, O., Meixner, C., Müller, M., Engelke, K.,... Nagel, A.M. (2022). Assessing muscle-specific potassium concentrations in human lower leg using potassium magnetic resonance imaging . NMR in Biomedicine . https://doi.org/10.1002/nbm.4819
Glang, F., Zaiss, M., Laun, F.B., Fabian, M.S., German, A., Khakzar, K.,... Scheffler, K. (2022). Linear projection-based CEST parameter estimation . NMR in Biomedicine . https://doi.org/10.1002/nbm.4697
Götz, M., Heiß, R., von Stengel, S., Roemer, F., Berger, J., Nagel, A.M.,... Kemmler, W. (2022). Spatial Distribution of Muscular Effects of Acute Whole-Body Electromyostimulation at the Mid-Thigh and Lower Leg-A Pilot Study Applying Magnetic Resonance Imaging . Sensors , 22 (24). https://doi.org/10.3390/s222410017
Heiß, R., Tan, L., Schmidt, S., Regensburger, A., Ewert, F., Mammadova, D.,... Knieling, F. (2022). Pulmonary Dysfunction after Pediatric COVID-19 . Radiology . https://doi.org/10.1148/radiol.221250
Hinsen, M., Heiß, R., Nagel, A.M., Levy, S., Uder, M., Bickelhaupt, S., & May, M. (2022). Lungenbildgebung in der Niederfeld-Magnetresonanztomographie . Radiologe . https://doi.org/10.1007/s00117-022-00996-7
Hunger, L., Rajput, J.R., Klein, K., Mennecke, A., Fabian, M., Schmidt, M.,... Zaiß, M. (2022). DeepCEST 7 T: Fast and homogeneous mapping of 7 T CEST MRI parameters and their uncertainty quantification . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.29520
Höger, S., Gast, L., Marty, B., Hotfiel, T., Bickelhaupt, S., Uder, M.,... Nagel, A.M. (2022). Sodium and quantitative hydrogen parameter changes in muscle tissue after eccentric exercise and in delayed-onset muscle soreness assessed with magnetic resonance imaging . NMR in Biomedicine . https://doi.org/10.1002/nbm.4840
Kamp, B., Frenken, M., Klein-Schmeink, L., Nagel, A.M., Wilms, L.M., Radke, K.L.,... Mueller-Lutz, A. (2022). Evaluation of Sodium Relaxation Times and Concentrations in the Achilles Tendon Using MRI . International Journal of Molecular Sciences , 23 (18). https://doi.org/10.3390/ijms231810890
Kapsner, L., Ohlmeyer, S., Folle, L., Laun, F.B., Nagel, A.M., Liebert, A.,... Bickelhaupt, S. (2022). Automated artifact detection in abbreviated dynamic contrast-enhanced (DCE) MRI-derived maximum intensity projections (MIPs) of the breast . European Radiology . https://doi.org/10.1007/s00330-022-08626-5
Kolwelter, J., Kannenkeril, D., Linz, P., Jung, S., Nagel, A.M., Bosch, A.,... Schmieder, R. (2022). The SGLT2 inhibitor empagliflozin reduces tissue sodium content in patients with chronic heart failure: results from a placebo-controlled randomised trial . Clinical Research in Cardiology . https://doi.org/10.1007/s00392-022-02119-7
Levy, S., Heiß, R., Grimm, R., Grodzki, D., Hadler, D., Voskrebenzev, A.,... Bickelhaupt, S. (2022). Free-Breathing Low-Field MRI of the Lungs Detects Functional Alterations Associated With Persistent Symptoms After COVID-19 Infection. Investigative Radiology , 57 (11), 742-751. https://doi.org/10.1097/RLI.0000000000000892
Levy, S., Herrler, J., Liebert, A., Tkotz, K., Fabian, M., Eisen, C.,... Nagel, A.M. (2022). Clinically compatible subject-specific dynamic parallel transmit pulse design for homogeneous fat saturation and water-excitation at 141657T: Proof-of-concept for 14165CEST MRI of the brain . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.29412
Meixner, C., Nagel, A.M., Höger, S., Gast, L., Wiesmüller, M., Uder, M.,... Heiß, R. (2022). Muscle perfusion and the effect of compression garments in delayed-onset muscle soreness assessed with arterial spin labeling magnetic resonance imaging . Quantitative Imaging in Medicine and Surgery . https://doi.org/10.21037/qims-21-1104
Mennecke, A., Khakzar, K.M., German, A., Herz, K., Fabian, M., Liebert, A.,... Zaiß, M. (2022). 7 tricks for 7 T CEST: Improving the reproducibility of multipool evaluation provides insights into the effects of age and the early stages of Parkinson's disease . NMR in Biomedicine . https://doi.org/10.1002/nbm.4717
Mueller, H.-P., Nagel, A.M., Keidel, F., Wunderlich, A., Hubers, A., Gast, L.,... Kassubek, J. (2022). Relaxation-weighted Na-23 magnetic resonance imaging maps regional patterns of abnormal sodium concentrations in amyotrophic lateral sclerosis . Therapeutic Advances in Chronic Disease , 13 . https://doi.org/10.1177/20406223221109480
Muller-Lutz, A., Kamp, B., Klein-Schmeink, L., Tsiami, S., Frenken, M., Nagel, A.M.,... Sewerin, P. (2022). QUANTITATIVE ANALYSIS BY SODIUM AND PROTON BASED 3-TESLA MR IMAGING OF THE ACHILLES TENDON . In ANNALS OF THE RHEUMATIC DISEASES (pp. 1784-1784). LONDON: BMJ PUBLISHING GROUP.
Müller, M., Egger, N., Sommer, S., Wilferth, T., Meixner, C., Laun, F.B.,... Nagel, A.M. (2022). Direct imaging of white matter ultrashort T2∗ components at 7 Tesla . Magnetic Resonance Imaging , 86 , 107-117. https://doi.org/10.1016/j.mri.2021.11.016
Pogarell, T., May, M., Nagel, A.M., Uder, M., & Heiß, R. (2022). Imaging of the musculoskeletal system using low-field magnetic resonance imaging . Radiologe . https://doi.org/10.1007/s00117-022-01000-y
Prasuhn, J., Goettlich, M., Grosser, S., Reuther, K., Ebeling, B., Bodemann, C.,... Bruggemann, N. (2022). Increased midbrain sodium levels in progressive supranuclear palsy . In EUROPEAN JOURNAL OF NEUROLOGY (pp. 498-498). HOBOKEN: WILEY.
Prasuhn, J., Gottlich, M., Grosser, S.S., Reuther, K., Ebeling, B., Munchau, A.,... Bruggemann, N. (2022). In Vivo Brain Sodium Disequilibrium in ATP1A3-Related Rapid-Onset Dystonia-Parkinsonism . Movement Disorders . https://doi.org/10.1002/mds.28954
Prasuhn, J., Göttlich, M., Grosser, S.S., Reuther, K., Ebeling, B., Bodemann, C.,... Brüggemann, N. (2022). Increased Subcortical Sodium Levels in Patients with Progressive Supranuclear Palsy . Biomedicines , 10 (7). https://doi.org/10.3390/biomedicines10071728
Ruck, L., Mennecke, A., Wilferth, T., Lachner, S., Müller, M., Egger, N.,... Nagel, A.M. (2022). Influence of image contrasts and reconstruction methods on the classification of multiple sclerosis-like lesions in simulated sodium magnetic resonance imaging . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.29476
Wilferth, T., Mennecke, A., Gast, L., Lachner, S., Müller, M., Rothhammer, V.,... Schmidt, M. (2022). Quantitative 7T sodium magnetic resonance imaging of the human brain using a 32-channel phased-array head coil: Application to patients with secondary progressive multiple sclerosis . NMR in Biomedicine . https://doi.org/10.1002/nbm.4806
Wilferth, T., Müller, M., Gast, L., Ruck, L., Meyerspeer, M., Kolkovsky, A.L.L.,... Nagel, A.M. (2022). Motion-corrected 23Na MRI of the human brain using interleaved 1H 3D navigator images . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.29221
Wilms, L.M., Radke, K.L., Latz, D., Thiel, T.A., Frenken, M., Kamp, B.,... Nebelung, S. (2022). UTE-T2* versus conventional T2* mapping to assess posterior cruciate ligament ultrastructure and integrity-an in-situ study . Quantitative Imaging in Medicine and Surgery , 12 (8), 4190-4201. https://doi.org/10.21037/qims-22-251
2021
Dahlmann, A., Linz, P., Zucker, I., Haag, V., Jantsch, J., Dienemann, T.,... Kopp, C. (2021). Reduction of Tissue Na+ Accumulation After Renal Transplantation . Kidney International Reports , 6 (9), 2338-2347. https://doi.org/10.1016/j.ekir.2021.06.022
Fetzer, S., Dibue, M., Nagel, A.M., & Trollmann, R. (2021). A systematic review of magnetic resonance imaging in patients with an implanted vagus nerve stimulation system . Neuroradiology . https://doi.org/10.1007/s00234-021-02705-y
German, A., Mennecke, A., Martin, J., Hanspach, J., Liebert, A., Herrler, J.,... Laun, F.B. (2021). Brain tissues have single-voxel signatures in multi-spectral MRI . NeuroImage , 234 . https://doi.org/10.1016/j.neuroimage.2021.117986
Ghasemikaram, M., Chaudry, O., Nagel, A.M., Uder, M., Jakob, F., Kemmler, W.,... Engelke, K. (2021). Effects of 16 months of high intensity resistance training on thigh muscle fat infiltration in elderly men with osteosarcopenia . GeroScience . https://doi.org/10.1007/s11357-020-00316-8
Hartmann, B., Müller, M., Seyler, L., Bäuerle, T., Wilferth, T., Avdievitch, N.,... Nagel, A.M. (2021). Feasibility of deuterium magnetic resonance spectroscopy of 3-O-Methylglucose at 7 Tesla . PLoS ONE , 16 (6 June). https://doi.org/10.1371/journal.pone.0252935
Heiß, R., Grodzki, D.M., Horger, W., Uder, M., Nagel, A.M., & Bickelhaupt, S. (2021). High-performance low field MRI enables visualization of persistent pulmonary damage after COVID-19 . Magnetic Resonance Imaging , 76 , 49-51. https://doi.org/10.1016/j.mri.2020.11.004
Heiß, R., Librimir, A., Lutter, C., Janka, R.M., Kuerten, S., Roemer, F.,... Bayer, T. (2021). Mri of finger pulleys at 7t—direct characterization of pulley ruptures in an ex vivo model . Diagnostics , 11 (7). https://doi.org/10.3390/diagnostics11071206
Heiß, R., Nagel, A.M., Laun, F.B., Uder, M., & Bickelhaupt, S. (2021). Low-Field Magnetic Resonance Imaging: A New Generation of Breakthrough Technology in Clinical Imaging . Investigative Radiology , 56 (11), 726-733. https://doi.org/10.1097/RLI.0000000000000805
Herrler, J., Liebig, P., Gumbrecht, R., Ritter, D., Schmitter, S., Maier, A.,... Nagel, A.M. (2021). Fast online-customized (FOCUS) parallel transmission pulses: A combination of universal pulses and individual optimization . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28643
Hotfiel, T., Höger, S., Nagel, A.M., Uder, M., Kemmler, W., Forst, R.,... Heiß, R. (2021). Multi-parametric analysis of below-knee compression garments on delayed-onset muscle soreness . International Journal of Environmental Research and Public Health , 18 (7). https://doi.org/10.3390/ijerph18073798
Jarraya, M., Heiß, R., Duryea, J., Nagel, A.M., Lynch, J.A., Guermazi, A.,... Roemer, F. (2021). Bone Structure Analysis of the Radius Using Ultrahigh Field (7T) MRI: Relevance of Technical Parameters and Comparison with 3T MRI and Radiography . Diagnostics , 11 (1). https://doi.org/10.3390/diagnostics11010110
Jarraya, M., Heiß, R., Duryea, J., Nagel, A.M., Lynch, J.A., Guermazi, A.,... Roemer, F. (2021). TRABECULAR SUBCHONDRAL BONE ANALYSIS OF THE DISTAL RADIUS AT ULTRA-HIGH FIELD (7T) MRI: COMPARISON WITH 3T MRI AND RADIOGRAPHY . In OSTEOARTHRITIS AND CARTILAGE (pp. S156-S157). OXFORD: ELSEVIER SCI LTD.
Kamp, B., Frenken, M., Henke, J.M., Abrar, D.B., Nagel, A.M., Gast, L.,... Mueller-Lutz, A. (2021). Quantification of Sodium Relaxation Times and Concentrations as Surrogates of Proteoglycan Content of Patellar CARTILAGE at 3T MRI . Diagnostics , 11 (12). https://doi.org/10.3390/diagnostics11122301
Kannenkeril, D., Jung, S., Harazny, J., Striepe, K., Ott, C., Dahlmann, A.,... Schmieder, R. (2021). Tissue sodium content correlates with hypertrophic vascular remodeling in type 2 diabetes . Journal of Diabetes and Its Complications , 35 (12). https://doi.org/10.1016/j.jdiacomp.2021.108055
Kolwelter, J., Bosch, A., Jung, S., Linz, P., Kannenkeril, D., Nagel, A.M.,... Schmieder, R. (2021). EFFECTS OF THE SGLT2 INHIBITOR EMPAGLIFLOZIN ON VASCULAR FUNCTION IN PATIENTS WITH CHRONIC HEART FAILURE . In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (pp. 1806-1806). NEW YORK: ELSEVIER SCIENCE INC.
Kolwelter, J., Kannenkeril, D., Linz, P., Jung, S., Nagel, A.M., Bosch, A.,... Schmieder, R. (2021). Reduced tissue sodium content is related to improvement of vascular function in patients with chronic heart failure treated with the SGLT2 inhibitor empagliflozin . In EUROPEAN HEART JOURNAL (pp. 795-795). OXFORD: OXFORD UNIV PRESS.
Kolwelter, J., Kannenkeril, D., Linz, P., Jung, S., Nagel, A.M., Bosch, A.,... Schmieder, R. (2021). THE SGLT2 INHIBITOR EMPAGLIFLOZIN REDUCES TISSUE SODIUM CONTENT IN PATIENTS WITH CHRONIC HEART FAILURE . In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (pp. 585-585). NEW YORK: ELSEVIER SCIENCE INC.
Kratzer, F.J., Flassbeck, S., Schmitter, S., Wilferth, T., Magill, A.W., Knowles, B.R.,... Nagel, A.M. (2021). 3D sodium (Na-23) magnetic resonance fingerprinting for time-efficient relaxometric mapping . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28873
Liebert, A., Tkotz, K., Herrler, J., Linz, P., Mennecke, A., German, A.,... Nagel, A.M. (2021). Whole-brain quantitative CEST MRI at 7T using parallel transmission methods and B1+ correction . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28745
Meixner, C., Eisen, C., Schmitter, S., Müller, M., Herrler, J., Hensel, B.,... Nagel, A.M. (2021). Hybrid B1+-shimming and gradient adaptions for improved pseudo-continuous arterial spin labeling at 7 Tesla . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28982
Mennecke, A., Nagel, A.M., Huhn, K., Linker, R., Schmidt, M., Rothhammer, V.,... Dörfler, A. (2021). Longitudinal Sodium MRI of Multiple Sclerosis Lesions: Is there Added Value of Sodium Inversion Recovery MRI . Journal of Magnetic Resonance Imaging . https://doi.org/10.1002/jmri.27832
Ruhm, L., Avdievich, N., Ziegs, T., Nagel, A.M., De Feyter, H.M., de Graaf, R.A., & Henning, A. (2021). Deuterium metabolic imaging in the human brain at 9.4 Tesla with high spatial and temporal resolution . NeuroImage , 244 . https://doi.org/10.1016/j.neuroimage.2021.118639
Schneider, T.M., Ma, J., Wagner, P., Behl, N., Nagel, A.M., Ladd, M.E.,... Straub, S. (2021). Multiparametric MRI for Characterization of the Basal Ganglia and the Midbrain . Frontiers in Neuroscience , 15 . https://doi.org/10.3389/fnins.2021.661504
Utzschneider, M., Müller, M., Gast, L., Lachner, S., Behl, N.G., Maier, A.,... Nagel, A.M. (2021). Towards accelerated quantitative sodium MRI at 7 T in the skeletal muscle: Comparison of anisotropic acquisition- and compressed sensing techniques . Magnetic Resonance Imaging , 75 , 72-88. https://doi.org/10.1016/j.mri.2020.09.019
Voelker, M.N., Kraff, O., Goerke, S., Laun, F.B., Hanspach, J., Pine, K.J.,... Quick, H.H. (2021). The traveling heads 2.0: Multicenter reproducibility of quantitative imaging methods at 7 Tesla . NeuroImage , 232 . https://doi.org/10.1016/j.neuroimage.2021.117910
Weber, M.-A., Seyler, L., & Nagel, A.M. (2021). 7 Tesla Chlorine (Cl-35) and Sodium (Na-23) MR Imaging of an Enchondroma . Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren . https://doi.org/10.1055/a-1472-6730
Zaric, O., Farr, A., Minarikova, L., Lachner, S., Asseryanis, E., Nagel, A.M.,... Trattnig, S. (2021). Tissue Sodium Concentration Quantification at 7.0-T MRI as an Early Marker for Chemotherapy Response in Breast Cancer: A Feasibility Study . Radiology , 299 (1), 63-72. https://doi.org/10.1148/radiol.2021201600
2020
Alhulail, A.A., Xia, P., Shen, X., Nichols, M., Volety, S., Farley, N.,... Emir, U.E. (2020). Fast in vivo Na-23 imaging and T-2* mapping using accelerated 2D-FID UTE magnetic resonance spectroscopic imaging at 3 T: Proof of concept and reliability study . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28576
Engelke, K., Chaudry, O., & Nagel, A.M. (2020). Quantitative MR-Bildgebung zur Charakterisierung der Skelettmuskulatur . Osteologie , 29 (2), 132-142. https://doi.org/10.1055/a-1130-4462
Gast, L., Volker, S., Utzschneider, M., Linz, P., Wilferth, T., Müller, M.,... Nagel, A.M. (2020). Combined imaging of potassium and sodium in human skeletal muscle tissue at 7 T . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28428
Gerhalter, T., Gast, L., Marty, B., Uder, M., Carlier, P.G., & Nagel, A.M. (2020). Assessing the variability of 23Na MRI in skeletal muscle tissue: Reproducibility and repeatability of tissue sodium concentration measurements in the lower leg at 3 T . NMR in Biomedicine . https://doi.org/10.1002/nbm.4279
Gerhalter, T., Marty, B., Gast, L., Porzelt, K., Heiß, R., Uder, M.,... Türk, M. (2020). Quantitative 1H and 23Na muscle MRI in Facioscapulohumeral muscular dystrophy patients . Journal of Neurology . https://doi.org/10.1007/s00415-020-10254-2
Hanspach, J., Nagel, A.M., Hensel, B., Uder, M., Koros, L., & Laun, F.B. (2020). Sample size estimation: Current practice and considerations for original investigations in MRI technical development studies . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28550
Heiß, R., Bayer, T., Janka, R.M., Brockhoff, M.-J., Uder, M., Nagel, A.M., & Roemer, F. (2020). IMPACT OF CLIMBING ACTIVITY AND AGE ON CARTILAGE STRUCTURAL COMPOSITION OF THE METACARPOPHALANGEAL AND PROXIMAL INTERPHALANGEAL JOINTS AS ASSESSED BY T2 RELAXOMETRY AT 7T MRI . In OSTEOARTHRITIS AND CARTILAGE (pp. S259-S259). Vienna, AT: OXFORD: ELSEVIER SCI LTD.
Kratzer, F.J., Flassbeck, S., Nagel, A.M., Behl, N.G., Knowles, B.R., Bachert, P.,... Schmitter, S. (2020). Sodium relaxometry using 23 Na MR fingerprinting: A proof of concept . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28316
Lachner, S., Utzschneider, M., Zaric, O., Minarikova, L., Ruck, L., Zbýň, Š.,... Nagel, A.M. (2020). Compressed sensing and the use of phased array coils in 23Na MRI: a comparison of a SENSE-based and an individually combined multi-channel reconstruction . Zeitschrift für Medizinische Physik . https://doi.org/10.1016/j.zemedi.2020.10.003
Müller-Lutz, A., Kamp, B., Nagel, A.M., Ljimani, A., Abrar, D., Schleich, C.,... Wittsack, H.J. (2020). Sodium MRI of human articular cartilage of the wrist: a feasibility study on a clinical 3T MRI scanner . Magnetic Resonance Materials in Physics Biology and Medicine . https://doi.org/10.1007/s10334-020-00856-2
Paech, D., Nagel, A.M., Schultheiss, M.N., Umathum, R., Regnery, S., Scherer, M.,... Niesporek, S.C. (2020). Quantitative dynamic oxygen 17 MRI at 7.0 T for the cerebral oxygen metabolism in glioma . Radiology , 295 (1), 181-189. https://doi.org/10.1148/radiol.2020191711
Roemer, F., Treutlein, C., Guermazi, A., Nagel, A.M., Schett, G., Uder, M., & Bäuerle, T. (2020). ASSESSMENT OF KNEE JOINT SYNOVITIS AT ULTRA-HIGH FIELD (7T) MRI: A MULTI-DIMENSIONAL APPROACH USING CONTRAST-ENHANCED AND NON-ENHANCED SEQUENCES . In OSTEOARTHRITIS AND CARTILAGE (pp. S297-S297). Vienna, AT: OXFORD: ELSEVIER SCI LTD.
Schüssler, S.C., Gerhalter, T., Abicht, A., Müller-Felber, W., Nagel, A.M., & Trollmann, R. (2020). Rare intronic mutation between Exon 62 and 63 (c.9225–285A>G) of the dystrophin gene associated with atypical BMD phenotype . Neuromuscular Disorders , 30 (8), 680-684. https://doi.org/10.1016/j.nmd.2020.06.003
Tomppert, A., Wüst, W., Wiesmüller, M., Heiß, R., Kopp, M., Nagel, A.M.,... May, M. (2020). Achieving high spatial and temporal resolution with perfusion MRI in the head and neck region using golden-angle radial sampling . European Radiology . https://doi.org/10.1007/s00330-020-07263-0
Treutlein, C., Bäuerle, T., Nagel, A.M., Guermazi, A., Kleyer, A., Simon, D.,... Roemer, F. (2020). Comprehensive assessment of knee joint synovitis at 7 T MRI using contrast-enhanced and non-enhanced sequences . BMC Musculoskeletal Disorders , 21 (1). https://doi.org/10.1186/s12891-020-3122-y
Utzschneider, M., Behl, N.G., Lachner, S., Gast, L., Maier, A., Uder, M., & Nagel, A.M. (2020). Correction to: Accelerated quantification of tissue sodium concentration in skeletal muscle tissue: quantitative capability of dictionary learning compressed sensing (Magnetic Resonance Materials in Physics, Biology and Medicine, (2020), 10.1007/s10334-019-00819-2) . Magnetic Resonance Materials in Physics Biology and Medicine . https://doi.org/10.1007/s10334-020-00835-7
Utzschneider, M., Behl, N.G.R., Lachner, S., Gast, L., Maier, A., Uder, M., & Nagel, A.M. (2020). T-2* Accelerated quantification of tissue sodium concentration in skeletal muscle tissue: quantitative capability of dictionary learning compressed sensing . Magnetic Resonance Materials in Physics Biology and Medicine . https://doi.org/10.1007/s10334-019-00819-2
Weber, M.-A., Nagel, A.M., Kan, H.E., & Wattjes, M.P. (2020). Quantitative Imaging in Muscle Diseases with Focus on Non-proton MRI and Other Advanced MRI Techniques . Seminars in Musculoskeletal Radiology , 24 (04), 402-412. https://doi.org/10.1055/s-0040-1712955
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My research is focussed on the development of efficient image acquisition, image reconstruction and post-processing techniques for ultra-high field and multi-nuclear magnetic resonance imaging. The aim is to develop and to evaluate these techniques for inter-disciplinary clinical research.
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