We study the mechanical behavior (such as stiffness, force generation and movements) of cells, tissue, and whole organisms, to help better understand mechanical aspects of diseases such as cancer, cardiovascular, musculoskeletal or inflammatory disorders.
Research projects
Cancer and immune cell biomechanics
Bioartificial muscle
3-D Tumor models for studying mechanisms of metastasis Formation
Novel hydrogels for tissue engineering and biofabrication
Measurement of cell mechanical properties as a diagnostic marker
Development of bioartificial skeletal and cardiac muscle tissues
Mechanisms of immune cell migration and invasion
Recent publications
2025
Böhringer, D., Cóndor, M., Bischof, L., Czerwinski, T., Gampl, N., Ngo, P.,... Gerum, R. (2025). Dynamic traction force measurements of migrating immune cells in 3D matrices . (Unpublished, Submitted).
Czerwinski, T., Bischof, L., Böhringer, D., Kara-Kocak, S., Strissel, P., Strick, R.,... Mark, C. (2025). Immune cells employ intermittent integrin-mediated traction forces for 3D migration . (Unpublished, Submitted).
2024
Goldmann, W. (2024). Durotaxis: A cause of organ fibrosis and metastatic cancer? Cell Biology International , 48 (5), 553-555. https://doi.org/10.1002/cbin.12156
Götz, T., Cong, X., Rauber, S., Angeli, M.R., Lang, E.W., Ramming, A., & Schmidkonz, C. (2024). A novel Slide-seq based image processing software to identify gene expression at the single cell level . Journal of Pathology Informatics , 15 . https://doi.org/10.1016/j.jpi.2024.100384
Horder, H., Böhringer, D., Endrizzi, N., Hildebrand, L.S., Cianciosi, A., Stecher, S.,... Blunk, T. (2024). Cancer cell migration depends on adjacent ASC and adipose spheroids in a 3D bioprinted breast cancer model . Biofabrication , 16 (3). https://doi.org/10.1088/1758-5090/ad57f7
Kamaleev, M., Kim, H., Denisov, N., & Tesler, A. (2024). Low pH-Induced Activation of Single-Atom Pt Sites on TiO2 for Enhanced Photocatalytic H2 Evolution . ACS Applied Energy Materials . https://doi.org/10.1021/acsaem.4c02480
LaRue, M., Iles, D., Labrousse, S., Fretwell, P., Ortega, D., Devane, E.,... Jenouvrier, S. (2024). Advances in remote sensing of emperor penguins: first multi-year time series documenting trends in the global population . Proceedings of the Royal Society of London, Series B: Biological Sciences , 291 (2018). https://doi.org/10.1098/rspb.2023.2067
Lonati, G.L., Hynes, N., Klymentieva, H., Warren, A., Zitterbart, D., Richter, S.,... Davies, K.T. (2024). Drone-based infrared thermography to measure the intranasal temperature of baleen whales . International Journal of Remote Sensing . https://doi.org/10.1080/01431161.2024.2399326
Magerl, A., Lemmel, H., Appel, M., Weißer, M., Kretzer, U., & Zobel, M. (2024). The promise of GaAs 200 in small-angle neutron scattering for higher resolution . Journal of Applied Crystallography , 57 , 1282-1287. https://doi.org/10.1107/S1600576724007246
Mazare, A.V., Hwang, I., & Tesler, A. (2024). Surface modification of TiO2 nanotubes via pre-loaded hydroxyapatite towards enhanced bioactivity . Materials Today Communications , 39 . https://doi.org/10.1016/j.mtcomm.2024.109216
Pandey, A., Nowakowski, P., Ureña Martin, C., Abu Ahmad, M., Edri, A., Toledo, E.,... Schvartzman, M. (2024). Membrane Fluctuation Model for Understanding the Effect of Receptor Nanoclustering on the Activation of Natural Killer Cells through Biomechanical Feedback . Nano Letters , 24 (18), 5395-5402. https://doi.org/10.1021/acs.nanolett.3c02815
Plekhanov, M.S., Thomä, S.L., Magerl, A., Appel, M., & Zobel, M. (2024). Quasi-Elastic Neutron Scattering of Citrate-Capped Iron Oxide Nanoparticles: Distinguishing between Ligand, Water, and Magnetic Dynamics . Journal of Physical Chemistry C . https://doi.org/10.1021/acs.jpcc.4c00479
Prado, L., Hayek, S., Mazare, A.V., Erceg, I., Sarau, G., Christiansen, S.,... Tesler, A. (2024). Aerophilic Surfaces for Sustained Corrosion Protection of Metals Underwater . Advanced Functional Materials . https://doi.org/10.1002/adfm.202407444
Pupillo, D., Bruns, M., Prado, L., Di Franco, F., Böhringer, D., Mazare, A.V.,... Tesler, A. (2024). Corrosion Resistance of Biodegradable Zinc Surfaces Enhanced by UV-Grafted Polydimethylsiloxane Coating . ACS Biomaterials Science and Engineering , 10 (8), 4891-4900. https://doi.org/10.1021/acsbiomaterials.4c00503
Raza, W., Tesler, A., Mazare, A.V., & Schmuki, P. (2024). Solar Light-Induced Photoelectrochemical H2 Generation Over Hierarchical TiO2 Nanotube Arrays Decorated with CdS Nanoparticles . Journal of The Electrochemical Society , 171 (6). https://doi.org/10.1149/1945-7111/ad52f2
Schilling, A., Gerum, R., Böhm, C., Rasheed, J., Metzner, C., Maier, A.,... Krauß, P. (2024). Deep learning based decoding of single local field potential events . NeuroImage , 297 . https://doi.org/10.1016/j.neuroimage.2024.120696
Tesler, A., Nurmi, H.A., Kolle, S., Prado, L., Karunakaran, B., Mazare, A.V.,... Goldmann, W. (2024). Predicting plastron thermodynamic stability for underwater superhydrophobicity . Communications Materials , 5 (1). https://doi.org/10.1038/s43246-024-00555-8
Trinh-Minh, T., Chen, C.-W., Tran-Manh, C., Li, Y.N., Zhu, H., Zhou, X.,... Distler, J.H.W. (2024). Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis . Journal of Clinical Investigation , 134 (10). https://doi.org/10.1172/JCI159884
Walter, T., Langbein, M., Blenk, P., Tesler, A., Prado, L., Bornstein, D.,... Vogel, N. (2024). Performance of environmentally friendly, liquid-infused coatings against biofouling: evaluation of macrofouling and microbially induced corrosion in freshwater environments . Journal of Materials Chemistry A . https://doi.org/10.1039/d4ta00741g
Winterl, A., Richter, S., Houstin, A., Barracho, T., Boureau, M., Cornec, C.,... Paranhos Zitterbart, D. (2024). Remote sensing of emperor penguin abundance and breeding success . Nature Communications , 15 (1). https://doi.org/10.1038/s41467-024-48239-8
Zrelski, M.M., Hösele, S., Kustermann, M., Fichtinger, P., Kah, D.-T.E., Athanasiou, I.,... Winter, L. (2024). Plectin Deficiency in Fibroblasts Deranges Intermediate Filament and Organelle Morphology, Migration, and Adhesion . Journal of Investigative Dermatology , 144 (3), 547-562.e9. https://doi.org/10.1016/j.jid.2023.08.020
2023
Bardon, G., Cristofari, R., Winterl, A., Barracho, T., Benoiste, M., Ceresa, C.,... Le Bohec, C. (2023). RFIDeep: Unfolding the potential of deep learning for radio-frequency identification . Methods in Ecology and Evolution , 14 (11), 2814-2826. https://doi.org/10.1111/2041-210X.14187
Böhringer, D., Bauer, A., Moravec, I., Bischof, L., Kah, D.-T.E., Mark, C.,... Fabry, B. (2023). Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility . Matrix Biology , 124 , 39-48. https://doi.org/10.1016/j.matbio.2023.11.004
Esser, T., Anspach, A., Muenzebrock, K., Kah, D.-T.E., Schrüfer, S., Schenk, J.,... Engel, F. (2023). Direct 3D‐Bioprinting of hiPSC‐derived Cardiomyocytes to Generate Functional Cardiac Tissues . Advanced Materials . https://doi.org/10.1002/adma.202305911
Fischer, L., & Thievessen, I. (2023). FUCCI Reporter Gene-Based Cell Cycle Analysis . In (pp. 371-385). Humana Press Inc..
Goldmann, W. (2023). Intermediate Filaments . De Gruyter.
Goldmann, W. (2023). Saw Palmetto may fight prostate cancer . Cell Biology International . https://doi.org/10.1002/cbin.12059
Goldmann, W. (2023). The Cytoskeleton . De Gruyter.
Mansour, J., Berwanger, C., Jung, M., Eichinger, L., Fabry, B., & Clemen, C.S. (2023). Clinorotation inhibits myotube formation by fluid motion, not by simulated microgravity . European Journal of Cell Biology , 102 (2). https://doi.org/10.1016/j.ejcb.2023.151330
Mühlberg, A., Ritter, P., Langer, S., Goossens, C., Nübler, S., Schneidereit, D.,... Kreiß, L. (2023). SEMPAI: a Self-Enhancing Multi-Photon Artificial Intelligence for Prior-Informed Assessment of Muscle Function and Pathology . Advanced Science . https://doi.org/10.1002/advs.202206319
Müller, S.J., Fabry, B., & Gekle, S. (2023). Predicting Cell Stress and Strain during Extrusion Bioprinting . Physical Review Applied , 19 (6). https://doi.org/10.1103/PhysRevApplied.19.064061
Müller, T., Liu, L., Czerwinski, T., Wiesinger, M., Dedden, M., Paap, E.-M.,... Bosch-Voskens, C. (2023). Increased Motility and Suppression of Ex Vivo–Expanded Regulatory T Cells Designed for Adoptive Transfer Therapy in Ulcerative Colitis . Cellular and Molecular Gastroenterology and Hepatology . https://doi.org/10.1016/j.jcmgh.2023.04.002
Prado, L., Böhringer, D., Mazare, A.V., Sotelo, L., Sarau, G., Christiansen, S.,... Tesler, A. (2023). Silicone-Based Lubricant-Infused Slippery Coating Covalently Bound to Aluminum Substrates for Underwater Applications . ACS Applied Materials and Interfaces . https://doi.org/10.1021/acsami.3c04508
Rederer, A., Rose, V., Krüger, R., Schmittutz, L., Swierzy, I., Fischer, L.,... Müller-Deile, J. (2023). Partner, Neighbor, Housekeeper and Dimension: 3D versus 2D Glomerular Co-Cultures Reveal Drawbacks of Currently Used Cell Culture Models . International Journal of Molecular Sciences , 24 (12). https://doi.org/10.3390/ijms241210384
Sunadome, K., Erickson, A.G., Kah, D.-T.E., Fabry, B., Adori, C., Kameneva, P.,... Adameyko, I. (2023). Directionality of developing skeletal muscles is set by mechanical forces . Nature Communications , 14 (1). https://doi.org/10.1038/s41467-023-38647-7
Tesler, A., Kolle, S., Prado, L., Thievessen, I., Böhringer, D., Backholm, M.,... Goldmann, W. (2023). Long-term stability of aerophilic metallic surfaces underwater . Nature Materials . https://doi.org/10.1038/s41563-023-01670-6
Winter, L., Staszewska-Daca, I., Zittrich, S., Elhamine, F., Zrelski, M.M., Schmidt, K.,... Wiche, G. (2023). Z-Disk-Associated Plectin (Isoform 1d): Spatial Arrangement, Interaction Partners, and Role in Filamin C Homeostasis . Cells , 12 (9). https://doi.org/10.3390/cells12091259
2022
An, R., Strissel, P., Al-Abboodi, M., Robering, J.W., Reakasame, S., Eckstein, M.,... Kengelbach-Weigand, A. (2022). An Innovative Arteriovenous (AV) Loop Breast Cancer Model Tailored for Cancer Research . Bioengineering , 9 (7). https://doi.org/10.3390/bioengineering9070280
Fischer, L., Nosratlo, M., Hast, K., Karakaya, E., Ströhlein, N., Esser, T.,... Thievessen, I. (2022). Calcium supplementation of bioinks reduces shear stress-induced cell damage during bioprinting . Biofabrication , 14 (4). https://doi.org/10.1088/1758-5090/ac84af
Folle, L., Tkotz, K., Gadjimuradov, F., Kapsner, L., Fabian, M., Bickelhaupt, S.,... Maier, A. (2022). Towards Super-resolution CEST MRI for Visualization of Small Structures . In Klaus Maier-Hein, Thomas M. Deserno, Heinz Handels, Andreas Maier, Christoph Palm, ThomasTolxdorff (Eds.), Bildverarbeitung für die Medizin 2022. (pp. 210-215). Wiesbaden: Springer Vieweg.
Folle, L., Tkotz, K., Liebert, A., Gadjimuradov, F., Kapsner, L., Fabian, M.,... Maier, A. (2022). Super-Resolution for CEST MRI . Poster presentation at Joint annual meeting ISMRM-ESMRMB ISMRT, London, England.
Gerum, R., Mirzahossein, E., Eroles, M., Elsterer, J., Mainka, A., Bauer, A.,... Fabry, B. (2022). Viscoelastic properties of suspended cells measured with shear flow deformation cytometry . eLife , 11 . https://doi.org/10.7554/eLife.78823
Goldmann, W. (2022). Proteinase 3 associated with Wegener's granulomatosis . Cell Biology International . https://doi.org/10.1002/cbin.11757
Gutt, J., Arndt, S., Barnes, D.K.A., Bornemann, H., Brey, T., Eisen, O.,... Piepenburg, D. (2022). Reviews and syntheses: A framework to observe, understand and projectecosystem response to environmental change in the East Antarctic SouthernOcean . Biogeosciences , 19 (22), 5313-5342. https://doi.org/10.5194/bg-19-5313-2022
Houstin, A., Paranhos Zitterbart, D., Heerah, K., Eisen, O., Planas-Bielsa, V., Fabry, B., & Le Bohec, C. (2022). Juvenile emperor penguin range calls for extended conservation measures in the Southern Ocean . Royal Society Open Science , 9 (8). https://doi.org/10.1098/rsos.211708
Houstin, A., Paranhos Zitterbart, D., Winterl, A., Richter, S., Planas-Bielsa, V., Chevallier, D.,... Le Bohec, C. (2022). Biologging of emperor penguins-Attachment techniques and associated deployment performance . PLoS ONE , 17 (8), e0265849-. https://doi.org/10.1371/journal.pone.0265849
Leistenschneider, C., Le Bohec, C., Eisen, O., Houstin, A., Neff, S., Primpke, S.,... Gerdts, G. (2022). No evidence of microplastic ingestion in emperor penguin chicks (Aptenodytes forsteri) from the Atka Bay colony (Dronning Maud Land, Antarctica) . Science of the Total Environment , 851 . https://doi.org/10.1016/j.scitotenv.2022.158314
Martínez Sánchez, L.d.C., Phuong Anh Ngo, ., Pradhan, R., Becker, L.S., Böhringer, D., Soteriou, D.,... Lopez Posadas, R. (2022). Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation . Gut . https://doi.org/10.1136/gutjnl-2021-325520
Metzner, C., Schilling, A., Traxdorf, M., Tziridis, K., Maier, A., Schulze, H., & Krauß, P. (2022). Classification at the accuracy limit: facing the problem of data ambiguity . Scientific Reports , 12 (1). https://doi.org/10.1038/s41598-022-26498-z
Peters, G., Jakubaß, B., Weidenfeller, K., Kniesburges, S., Böhringer, D., Wendler, O.,... Semmler, M. (2022). Synthetic mucus for an ex vivo phonation setup: Creation, application, and effect on excised porcine larynges . Journal of the Acoustical Society of America , 152 (6), 3245-3259. https://doi.org/10.1121/10.0015364
Prechova, M., Adamova, Z., Schweizer, A.L., Maninova, M., Bauer, A., Kah, D.-T.E.,... Gregor, M. (2022). Plectin-mediated cytoskeletal crosstalk controls cell tension and cohesion in epithelial sheets . The Journal of Cell Biology , 221 (3). https://doi.org/10.1083/jcb.202105146
Schmid, R., Schmidt, S., Detsch, R., Horder, H., Blunk, T., Schrüfer, S.,... Kengelbach-Weigand, A. (2022). A new printable alginate / hyaluronic acid / gelatin hydrogel suitable for biofabrication of in vitro and in vivo metastatic melanoma models . Advanced Functional Materials , Volume 32 (Issue 2). https://doi.org/10.1002/adfm.202107993
Schween, L., Mücke, N., Portet, S., Goldmann, W., Herrmann, H., & Fabry, B. (2022). Dual-wavelength stopped-flow analysis of the lateral and longitudinal assembly kinetics of vimentin . Biophysical Journal . https://doi.org/10.1016/j.bpj.2022.09.008
Sivakumar, S., Schmid, R., Wieland, A., Strissel, P., Strick, R., Fischer, L.,... Kengelbach-Weigand, A. (2022). Role of Fiber Thickness and Surface Treatment of Electrospun Polycaprolactone Matrices on the Growth of Different Breast Cancer‐Associated Cells . Advanced Materials Interfaces , 2101808. https://doi.org/10.1002/admi.202101808
Tesler, A., Prado, L., Thievessen, I., Mazare, A.V., Schmuki, P., Virtanen, S., & Goldmann, W. (2022). Nontoxic Liquid-Infused Slippery Coating Prepared on Steel Substrates Inhibits Corrosion and Biofouling Adhesion . ACS Applied Materials and Interfaces , 14 (25), 29386-29397. https://doi.org/10.1021/acsami.2c04960
Thievessen, I., Suhr, F., Vergarajauregui, S., Böttcher, R.T., Brixius, K., Rosenberger, G.,... Dewald, O. (2022). The focal adhesion protein β-parvin controls cardiomyocyte shape and sarcomere assembly in response to mechanical load . Current Biology , 32 (14), 3033-3047.e9. https://doi.org/10.1016/j.cub.2022.05.047
2021
Andree, V., Niopek, D., Müller, C., Eiselt, J.-P., Foh, N., Rzany, A., & Hensel, B. (2021). Influence of drying methods on the physical properties of bacterial nanocellulose . Materials Research Express , 8 (2). https://doi.org/10.1088/2053-1591/abe016
Angeloni, M., Thievessen, I., Engel, F., Magni, P., & Ferrazzi, F. (2021). Functional genomics meta-analysis to identify gene set enrichment networks in cardiac hypertrophy . Biological Chemistry . https://doi.org/10.1515/hsz-2020-0378
Bauer, A., Prechová, M., Fischer, L., Thievessen, I., Gregor, M., & Fabry, B. (2021). pyTFM: A tool for traction force and monolayer stress microscopy . PLoS Computational Biology , 17 (6). https://doi.org/10.1371/journal.pcbi.1008364
Bönsel, F., Krauß, P., Metzner, C., & Yamakou, M. (2021). Control of noise-induced coherent oscillations in three-neuron motifs . Cognitive Neurodynamics , 16 , 941-960. https://doi.org/10.1007/s11571-021-09770-2
Eroles, M., Gerum, R., Fabry, B., & Rico, F. (2021). Fast phenotyping of monocytes mechanics under the cytokine storm . In EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (pp. 133-133). NEW YORK: SPRINGER.
Führes, T., Riexinger, A., Loh, M., Martin, J., Wetscherek, A., Kuder, T.A.,... Laun, F.B. (2021). Echo time dependence of biexponential and triexponential intravoxel incoherent motion parameters in the liver . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28996
Goldmann, W. (2021). Biosensitive and antibacterial coatings on metallic material for medical applications . Cell Biology International . https://doi.org/10.1002/cbin.11604
Hahn, L., Beudert, M., Gutmann, M., Kessler, L., Stahlhut, P., Fischer, L.,... Luxenhofer, R. (2021). From Thermogelling Hydrogels toward Functional Bioinks: Controlled Modification and Cytocompatible Crosslinking . Macromolecular Bioscience . https://doi.org/10.1002/mabi.202100122
Hazur, J., Endrizzi, N., Schubert, D.W., Boccaccini, A.R., & Fabry, B. (2021). Stress relaxation amplitude of hydrogels determines migration, proliferation, and morphology of cells in 3-D culture . Biomaterials Science . https://doi.org/10.1039/d1bm01089a
Horder, H., Lasheras, M.G., Grummel, N., Nadernezhad, A., Herbig, J., Erguen, S.,... Blunk, T. (2021). Bioprinting and Differentiation of Adipose-Derived Stromal Cell Spheroids for a 3D Breast Cancer-Adipose Tissue Model . Cells , 10 (4). https://doi.org/10.3390/cells10040803
Kah, D.-T.E., Winterl, A., Přechová, M., Schöler, U., Schneider, W., Friedrich, O.,... Fabry, B. (2021). A low-cost uniaxial cell stretcher for six parallel wells . HardwareX , 9 . https://doi.org/10.1016/j.ohx.2020.e00162
Kappelmann-Fenzl, M., Schmidt, S., Fischer, S., Schmid, R., Lämmerhirt, L., Fischer, L.,... Boßerhoff, A.K. (2021). Molecular changes induced in melanoma by cell culturing in 3D alginate hydrogels . Cancers , 13 (16), 72-72. https://doi.org/10.3390/cancers13164111
Krausova, A., Buresova, P., Sarnova, L., Oyman-Eyrilmez, G., Skarda, J., Wohl, P.,... Gregor, M. (2021). Plectin ensures intestinal epithelial integrity and protects colon against colitis . Mucosal Immunology . https://doi.org/10.1038/s41385-021-00380-z
Krauß, P., Metzner, C., Joshi, N., Schulze, H., Traxdorf, M., Maier, A., & Schilling, A. (2021). Analysis and visualization of sleep stages based on deep neural networks . Neurobiology of Sleep and Circadian Rhythms , 10 . https://doi.org/10.1016/j.nbscr.2021.100064
Labrousse, S., Iles, D., Viollat, L., Fretwell, P., Trathan, P.N., Paranhos Zitterbart, D.,... Larue, M. (2021). Quantifying the causes and consequences of variation in satellite-derived population indices: a case study of emperor penguins . Remote Sensing in Ecology and Conservation . https://doi.org/10.1002/rse2.233
Lehenberger, M., Foh, N., Göttlein, A., Six, D., & Biedermann, P.H. (2021). Nutrient-Poor Breeding Substrates of Ambrosia Beetles Are Enriched With Biologically Important Elements . Frontiers in Microbiology , 12 . https://dx.doi.org/10.3389/fmicb.2021.664542
Liebert, A., Tkotz, K., Herrler, J., Linz, P., Mennecke, A., German, A.,... Nagel, A.M. (2021). Whole-brain quantitative CEST MRI at 7T using parallel transmission methods and B1+ correction . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28745
Maqbool, M., Nawaz, Q., Ur Rehman, M.A., Cresswell, M., Jackson, P., Hurle, K.,... Boccaccini, A.R. (2021). Synthesis, characterization, antibacterial properties, and in vitro studies of selenium and strontium co-substituted hydroxyapatite . International Journal of Molecular Sciences , 22 (8). https://doi.org/10.3390/ijms22084246
Metzner, C., Hörsch, F., Mark, C., Czerwinski, T., Winterl, A., Voskens, C., & Fabry, B. (2021). Detecting long-range interactions between migrating cells . Scientific Reports , 11 (1). https://doi.org/10.1038/s41598-021-94458-0
Owen, K., Saeki, K., Warren, J.D., Bocconcelli, A., Wiley, D.N., Ohira, S.I.,... Paranhos Zitterbart, D. (2021). Natural dimethyl sulfide gradients would lead marine predators to higher prey biomass . Communications Biology , 4 (1). https://doi.org/10.1038/s42003-021-01668-3
Paripovic, D., Hartmann, L., Steinrück, H.-G., Magerl, A., Li-Destri, G., Fontana, Y.,... Frauenrath, H. (2021). Lamellar carbon-aluminosilicate nanocomposites with macroscopic orientation . Nanoscale . https://doi.org/10.1039/d1nr00807b
Peters, G., Wendler, O., Böhringer, D., Gostian, A.O., Müller, S., Canziani, H.,... Döllinger, M. (2021). Human laryngeal mucus from the vocal folds: Rheological characterization by particle tracking microrheology and oscillatory shear rheology . Applied Sciences , 11 (7). https://doi.org/10.3390/app11073011
Riexinger, A., Laun, F.B., Hoeger, S.A., Wiesmüller, M., Uder, M., Hensel, B.,... Heiß, R. (2021). Effect of compression garments on muscle perfusion in delayed-onset muscle soreness: A quantitative analysis using intravoxel incoherent motion MR perfusion imaging . NMR in Biomedicine . https://doi.org/10.1002/nbm.4487
Schmid, R., Schmidt, S., Detsch, R., Horder, H., Blunk, T., Schrüfer, S.,... Kengelbach-Weigand, A. (2021). A new printable alginate / hyaluronic acid / gelatin hydrogel suitable for biofabrication of in vitro and in vivo metastatic melanoma models . Advanced Functional Materials . https://doi.org/10.1002/adfm.202107993
Schmid, R., Schmidt, S., Detsch, R., Horder, H., Blunk, T., Schrüfer, S.,... Kengelbach-Weigand, A. (2021). A New Printable Alginate/Hyaluronic Acid/Gelatin Hydrogel Suitable for Biofabrication of In Vitro and In Vivo Metastatic Melanoma Models . Advanced Functional Materials . https://doi.org/10.1002/adfm.202107993
Sonnleitner, D., Schaefer, N., Wieland, A., Fischer, L., Pasberg, P., Thievessen, I., & Lang, G. (2021). PCL micro-dumbbells - A new class of polymeric particles reveals morphological biofunctionality . Applied Materials Today , 24 . https://doi.org/10.1016/j.apmt.2021.101097
Spörrer, M., Kah, D.-T.E., Gerum, R., Reischl, B., Huraskin, D., Dessalles, C.A.,... Fabry, B. (2021). The desmin mutation R349P increases contractility and fragility of stem cell-generated muscle micro-tissues . Neuropathology and Applied Neurobiology . https://doi.org/10.1111/nan.12784
Tesler, A., Prado, L., Khusniyarov, M., Thievessen, I., Mazare, A.V., Fischer, L.,... Schmuki, P. (2021). A One-Pot Universal Approach to Fabricate Lubricant-Infused Slippery Surfaces on Solid Substrates . Advanced Functional Materials . https://doi.org/10.1002/adfm.202101090
2020
Aydemir, T., Liverani, L., Pastore, J.I., Ceré, S.M., Goldmann, W., Boccaccini, A.R., & Ballarre, J. (2020). Functional behavior of chitosan/gelatin/silica-gentamicin coatings by electrophoretic deposition on surgical grade stainless steel . Materials Science and Engineering C , 115 . https://doi.org/10.1016/j.msec.2020.111062
Böhringer, D., Mark, C., Grummel, N., Strissel, P., Strick, R., Grundy, T.J.,... Fabry, B. (2020). Collective Synchronization of Contractile Forces in Tumor Spheroids . In BIOPHYSICAL JOURNAL (pp. 606A-606A). San Diego, CA, US: CAMBRIDGE: CELL PRESS.
Böhringer, D., Rausch, M., Steinmann, M., Schrüfer, S., Schubert, D.W., Haertl, A.,... Fabry, B. (2020). Measurement of Skeletal Muscle Fiber Contractility with High-Speed Traction Microscopy . In BIOPHYSICAL JOURNAL (pp. 280A-280A). San Diego, CA, US: CAMBRIDGE: CELL PRESS.
Chatzifrangkeskou, M., Kah, D.-T.E., Lange, J., Goldmann, W., & Muchir, A. (2020). Mutated lamin A modulates stiffness in muscle cells . Biochemical and Biophysical Research Communications . https://doi.org/10.1016/j.bbrc.2020.05.102
Ciraldo, F., Arango-Ospina, M., Goldmann, W.H., Beltran, A.M., Detsch, R., Gruenewald, A.,... Boccaccini, A.R. (2020). Fabrication and characterization of Ag- and Ga-doped mesoporous glass-coated scaffolds based on natural marine sponges with improved mechanical properties . Journal of Biomedical Materials Research Part A . https://doi.org/10.1002/jbm.a.37123
Czerwinski, T., Mark, C., Roessner, S., Bosch-Voskens, C., Bhattacharjee, T., Angelini, T.E., & Fabry, B. (2020). Mesenchymal-Like Migration Strategies of Immune Cells in a 3D Environment . In BIOPHYSICAL JOURNAL (pp. 600A-600A). San Diego, CA, US: CAMBRIDGE: CELL PRESS.
Gast, L., Volker, S., Utzschneider, M., Linz, P., Wilferth, T., Müller, M.,... Nagel, A.M. (2020). Combined imaging of potassium and sodium in human skeletal muscle tissue at 7 T . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28428
Gerum, R., Erpenbeck, A., Krauß, P., & Schilling, A. (2020). Sparsity through evolutionary pruning prevents neuronal networks from overfitting . Neural Networks , 128 , 305-312. https://doi.org/10.1016/j.neunet.2020.05.007
Hanspach, J., Nagel, A.M., Hensel, B., Uder, M., Koros, L., & Laun, F.B. (2020). Sample size estimation: Current practice and considerations for original investigations in MRI technical development studies . Magnetic Resonance in Medicine . https://doi.org/10.1002/mrm.28550
Hasanzadeh Kafshgari, M., & Goldmann, W. (2020). Insights into Theranostic Properties of Titanium Dioxide for Nanomedicine . Nano-Micro Letters , 12 (1). https://doi.org/10.1007/s40820-019-0362-1
Kah, D.-T.E., Dürrbeck, C., Schneider, W., Fabry, B., & Gerum, R. (2020). High-Force Magnetic Tweezers with Hysteresis-Free Force Feedback . Biophysical Journal . https://doi.org/10.1016/j.bpj.2020.05.018
Lacaria, L., Lange, J., Goldmann, W., Rico, F., & Alonso, J.L. (2020). Corrigendum to “alphavbeta3 integrin expression increases elasticity in human melanoma cells” [Biochem. Biophys. Res. Commun. 525 (2020)](S0006291X20304472)(10.1016/j.bbrc.2020.02.156) . Biochemical and Biophysical Research Communications . https://doi.org/10.1016/j.bbrc.2020.08.001
Lacaria, L., Lange, J., Goldmann, W., Rico, F., & Alonso, J.L. (2020). αvβ3 integrin expression increases elasticity in human melanoma cells . Biochemical and Biophysical Research Communications . https://doi.org/10.1016/j.bbrc.2020.02.156
Lachner, S., Utzschneider, M., Zaric, O., Minarikova, L., Ruck, L., Zbýň, Š.,... Nagel, A.M. (2020). Compressed sensing and the use of phased array coils in 23Na MRI: a comparison of a SENSE-based and an individually combined multi-channel reconstruction . Zeitschrift für Medizinische Physik . https://doi.org/10.1016/j.zemedi.2020.10.003
Lapa, A., Cresswell, M., Campbell, I., Jackson, P., Goldmann, W.H., Detsch, R., & Boccaccini, A.R. (2020). Gallium- and Cerium-Doped Phosphate Glasses with Antibacterial Properties for Medical Applications . Advanced Engineering Materials . https://doi.org/10.1002/adem.201901577
Mark, C., Czerwinksi, T., Roessner, S., Mainka, A., Hoersch, F., Heublein, L.,... Bosch-Voskens, C. (2020). Cryopreservation reduces the Ability to migrate and the Cytotoxicity of natural Killer Cells in 3D: Possible Effects on cellular Immunotherapy . In JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT (pp. 68-68). HOBOKEN: WILEY.
Mark, C., Czerwinski, T., Roessner, S., Mainka, A., Hörsch, F., Heublein, L.,... Bosch-Voskens, C. (2020). Cryopreservation impairs 3-D migration and cytotoxicity of natural killer cells . Nature Communications , 11 (1). https://doi.org/10.1038/s41467-020-19094-0
Mark, C., Grundy, T.J., Strissel, P., Böhringer, D., Grummel, N., Gerum, R.,... Fabry, B. (2020). Collective forces of tumor spheroids in three-dimensional biopolymer networks . eLife , 9 . https://doi.org/10.7554/eLife.51912
Mark, C., Grundy, T.J., Strissel, P., Böhringer, D., Grummel, N., Gerum, R.,... Fabry, B. (2020). Correction: Collective forces of tumor spheroids in three-dimensional biopolymer networks. eLife , 9 . https://doi.org/10.7554/eLife.59538
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Müller, S.J., Mirzahossein, E., Iftekhar, E.N., Bächer, C., Schrüfer, S., Schubert, D.W.,... Gekle, S. (2020). Flow and hydrodynamic shear stress inside a printing needle during biofabrication . PLoS ONE , 15 (7), e0236371-. https://doi.org/10.1371/journal.pone.0236371
Naganawa, S., Nakane, T., Kawai, H., Taoka, T., Kawaguchi, H., Maruyama, K.,... Sone, M. (2020). Detection of iv-gadolinium leakage from the cortical veins into the CSF using MR fingerprinting . Magnetic Resonance in Medical Sciences , 19 (2), 141-146. https://dx.doi.org/10.2463/mrms.mp.2019-0048
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We study the mechanical behavior (such as stiffness, force generation and movements) of cells, tissue, and whole organisms, to help better understand mechanical aspects of diseases such as cancer, cardiovascular, musculoskeletal or inflammatory disorders.
Research projects
EXIST-Forschungstransfer - BreatheAssist ist ein neuartiges Intensiv-Beatmungsgerät, das es Patienten erlaubt, frühzeitig wieder selbst zu atmen und drängende Probleme wie Desynchronisation, unnatürliche Atemarbeit und geräteinduzierte Lungenschäden vermeiden soll. Dies ermöglicht damit erstmals eine maximal lungenschonendeSpontanatmung.
(Third Party Funds Single)
Funding source: Bundesministerium für Wirtschaft und Klimaschutz (BMWK)
2025
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2023
2022
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2020
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