Prof. Dr. Hans-Ulrich Prokosch

Research topics

Architecture, conception and management of state of the art hospital information systems
Telematic networking of the healthcare system
Evaluation of information systems in health care
Computer-based learning systems
WAIN knowledge base for a general drug information system with focus on intensive care medicine and nephrology
German Biobank Alliance: Development, testing and application of comprehensive, generic standards, products and solutions to enable the integration of German biobanks into BBMRI (Biobanking and Biomolecular Ressources Research Infrastructure)
MetropolMediplan 2016: Nationwide medication plan for Germany with cross-sectoral exchange of medication data between doctors and pharmacists

INTERPOLAR: WP3 - Interventionelle Studie: Universitätsklinikum Erlangen

(Third Party Funds Group – Sub project)

Overall project: INTERPOLAR - Medizininformatik-Use Case "INTERventional POLypharmacy - drug interActions - Risks"
Project leader: Hans-Ulrich Prokosch, Thomas Ganslandt, Frank Dörje
Term: 1. January 2023 - 31. December 2026
Acronym: INTERPOLAR
Funding source: BMBF / Verbundprojekt

→More information

2025

Apfelbacher, T., Koçman, S., Negash, S., Manuilova, I., Mang, J.M., Papon, H.,... Christoph, J. (2025). Utilization of Broad Consent as an Effective Instrument for Study Recruitment. In Rainer Röhrig, Thomas Ganslandt, Klaus Jung, Ann-Kristin Kock-Schoppenhauer, Jochem König, Ulrich Sax, Martin Sedlmayr, Cord Spreckelsen, Antonia Zapf (Eds.), German Medical Data Sciences 2025: GMDS Illuminates Health. (pp. 73-80). Amsterdam: IOS Press.
Iancu, A., Bauer, J., May, M., Prokosch, H.-U., Dörfler, A., Uder, M., & Kapsner, L. (2025). Large-Scale Integration of DICOM Metadata into HL7-FHIR for Medical Research. Methods of Information in Medicine. https://doi.org/10.1055/a-2521-4250
Kampf, M.O., Prokosch, H.-U., Gulden, C., Kraska, D., Ganslandt, T., & Seuchter, S.A. (2025). Evaluation of a DIC Broad Consent Cohort. In Elisavet Andrikopoulou, Parisis Gallos, Theodoros N. Arvanitis, Rosalynn Austin, Arriel Benis, Ronald Cornet, Panagiotis Chatzistergos, Alexander Dejaco, Linda Dusseljee-Peute, Alaa Mohasseb, Pantelis Natsiavas, Haythem Nakkas, Philip Scott (Eds.), Intelligent Health Systems – From Technology to Data and Knowledge. (pp. 492-496). IOS Press.
Koçman, S., Köster, H., Gulden, C., Kapsner, L., Engel, I., Prokosch, H.-U., & Mang, J.M. (2025). Is Research Data Trustworthy? A Quality Comparison Between FHIR, Trinetx and Clinical Data Sources. In Elisavet Andrikopoulou, Parisis Gallos, Theodoros N. Arvanitis, Rosalynn Austin, Arriel Benis, Ronald Cornet, Panagiotis Chatzistergos, Alexander Dejaco, Linda Dusseljee-Peute, Alaa Mohasseb, Pantelis Natsiavas, Haythem Nakkas, Philip Scott (Eds.), Intelligent Health Systems – From Technology to Data and Knowledge. (pp. 703-707). IOS Press.
Weidinger, F., Dietzel, N., Grässel, E., Prokosch, H.-U., & Kolominsky-Rabas, P. (2025). Using Health Information Resources for People With Cognitive Impairment (digiDEM Bayern): Registry-Based Cohort Study. JMIR Formative Research, 9. https://doi.org/10.2196/54460
Wen, Y., Choo, V.Y., Eil, J.H., Thun, S., dos Santos, D.P., Kast, J.,... Hosch, R. (2025). Exchange of Quantitative Computed Tomography Assessed Body Composition Data Using Fast Healthcare Interoperability Resources as a Necessary Step Toward Interoperable Integration of Opportunistic Screening Into Clinical Practice: Methodological Development Study. Journal of Medical Internet Research, 27. https://doi.org/10.2196/68750
Yilmaz, G., Mang, J.M., Metzler, M., Prokosch, H.-U., Rauh, M., & Zierk, J. (2025). PED-DATA: A Privacy-Preserving Framework for Data-Driven, Pediatric Multi-Center Studies. In Rainer Röhrig, Thomas Ganslandt, Klaus Jung, Ann-Kristin Kock-Schoppenhauer, Jochem König, Ulrich Sax, Martin Sedlmayr, Cord Spreckelsen, Antonia Zapf (Eds.), German Medical Data Sciences 2025: GMDS Illuminates Health. (pp. 307-317). IOS Press.
Zeiler, M., Dietzel, N., Haug, F., Haug, J., Kammerer, K., Pryss, R.,... Prokosch, H.-U. (2025). A User-Centered Design Approach for a Screening App for People With Cognitive Impairment (digiDEM-SCREEN): Development and Usability Study. JMIR Human Factors, 12. https://doi.org/10.2196/65022
Zeiler, M., Dietzel, N., Kammerer, K., Frick, U., Pryss, R., Heuschmann, P.,... Kolominsky-Rabas, P. (2025). Digital screening tool for the assessment of cognitive impairment in unsupervised setting - DigiDEM-SCREEN: Study protocol for a validation study. BMJ Open, 15(1). https://doi.org/10.1136/bmjopen-2024-087256
Ziegler, J., Erpenbeck, M.P., Fuchs, T., Saibold, A., Volkmer, P.C., Schmidt, G.,... Gulden, C. (2025). Bridging Data Silos in Oncology with Modular Software for Federated Analysis on Fast Healthcare Interoperability Resources: Multisite Implementation Study. Journal of Medical Internet Research, 27. https://doi.org/10.2196/65681
Ziegler, J., Fischer, C., Volkmer, P.C., Erpenbeck, M.P., Mang, J.M., Ganslandt, T.,... Gulden, C. (2025). Assuring End-to-End Data Quality for Analytics on FHIR. In Martin Baumgartner, Dieter Hayn, Bernhard Pfeifer, Günter Schreier (Eds.), dHealth 2025. (pp. 57-62). IOS Press.

2024

Apfelbacher, T., Koçman, S.E., Prokosch, H.-U., & Christoph, J. (2024). A Governance Framework for the Implementation and Operation of AI Applications in a University Hospital. In John Mantas, Arie Hasman, George Demiris, Kaija Saranto, Michael Marschollek, Theodoros N. Arvanitis, Ivana Ognjanovic, Arriel Benis, Parisis Gallos, Emmanouil Zoulias, Elisavet Andrikopoulou (Eds.), Digital Health and Informatics Innovations for Sustainable Health Care Systems. Proceedings of MIE 2024 (pp. 776-780). Athens, GR: Amsterdam: IOS Press.
Blasini, R., Strantz, C., Gulden, C., Helfer, S., Lidke, J., Prokosch, H.-U.,... Schneider, H. (2024). Evaluation of Eligibility Criteria Relevance for the Purpose of IT-Supported Trial Recruitment: Descriptive Quantitative Analysis. JMIR Formative Research, 8(1). https://doi.org/10.2196/49347
Boeker, M., Zöller, D., Blasini, R., Macho, P., Helfer, S., Behrens, M.,... Gulden, C. (2024). Effectiveness of IT-supported patient recruitment: study protocol for an interrupted time series study at ten German university hospitals. Trials, 25(1). https://doi.org/10.1186/s13063-024-07918-z
Engels, C., Kern, J., Dudová, Z., Deppenwiese, N., Kiel, A., Kroll, B.,... Prokosch, H.-U. (2024). The sample locator: A federated search tool for biosamples and associated data in Europe using HL7 FHIR. Computers in Biology and Medicine, 180. https://doi.org/10.1016/j.compbiomed.2024.108941
Gulden, C., Macho, P., Reinecke, I., Strantz, C., Prokosch, H.-U., & Blasini, R. (2024). recruIT: A cloud-native clinical trial recruitment support system based on Health Level 7 Fast Healthcare Interoperability Resources (HL7 FHIR) and the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM). Computers in Biology and Medicine, 174. https://doi.org/10.1016/j.compbiomed.2024.108411
Kapsner, L., Feißt, M., Purbojo, A., Prokosch, H.-U., Ganslandt, T., Dittrich, S.,... Wällisch, W. (2024). Using Machine Learning and Feature Importance to Identify Risk Factors for Mortality in Pediatric Heart Surgery. Diagnostics, 14(22). https://doi.org/10.3390/diagnostics14222587
Kleinert, P., Gebhardt, M., Buckow, K., Gründner, J., Ganslandt, T., Prokosch, H.-U., & Semler, S.C. (2024). Germany's Approach for the Secondary Use of Federated Real-World Data in the German Portal for Medical Research Data. In John Mantas, Arie Hasman, George Demiris, Kaija Saranto, Michael Marschollek, Theodoros N. Arvanitis, Ivana Ognjanovic, Arriel Benis, Parisis Gallos, Emmanouil Zoulias, Elisavet Andrikopoulou (Eds.), Studies in Health Technology and Informatics (pp. 1704-1708). Athens, GRC: IOS Press BV.
Krefting, D., Bavendiek, U., Fischer, J., Marx, G., Molinnus, D., Panholzer, T.,... Sedlmayr, M. (2024). Die digitalen Fortschrittshubs Gesundheit – Gemeinsame Datennutzung über die Universitätsmedizin hinaus. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 67(6), 701-709. https://doi.org/10.1007/s00103-024-03883-9
Laininger, L., Dietzel, N., Grässel, E., Prokosch, H.-U., & Kolominsky-Rabas, P. (2024). Impact of social network composition on cognitive decline: Digital Dementia Registry Bavaria (digiDEM Bayern). PLoS ONE, 19(7). https://doi.org/10.1371/journal.pone.0306447
Pilgram, L., Meurers, T., Malin, B., Schaeffner, E., Eckardt, K.U., Prasser, F.,... Nadal, J. (2024). The Costs of Anonymization: Case Study Using Clinical Data. Journal of Medical Internet Research, 26(1). https://doi.org/10.2196/49445
Riedel, A., Deppenwiese, N., Thiele, L., Prokosch, H.-U., & Herzog, A. (2024). Development of a SNOMED CT Mapping Process and Tool at a Data Integration Centre - Lessons Learned. In Rainer Rohrig, Niels Grabe, Ursula Hertha Hubner, Klaus Jung, Ulrich Sax, Carsten Oliver Schmidt, Martin Sedlmayr, Antonia Zapf (Eds.), Studies in Health Technology and Informatics (pp. 160-170). Dresden, DE: IOS Press BV.
Rödle, W., Prokosch, H.-U., Neumann, E., Toni, I., Haering-Zahn, J., Neubert, A., & Eberl, S. (2024). Creating a Medication Therapy Observational Research Database from an Electronic Medical Record: Challenges and Data Curation. Applied Clinical Informatics, 15(1), 111-118. https://doi.org/10.1055/s-0043-1777741
Schmitt, J., Ihle, P., Schoffer, O., Reese, J.P., Ortmann, S., Swart, E.,... Zeynalova, S. (2024). Datennutzung für eine bessere Gesundheitsversorgung–Plädoyer für eine kooperative Forschungsdatenplattform der gesetzlichen und privaten Krankenversicherung und dem Netzwerk Universitätsmedizin (NUM). Gesundheitswesen. https://doi.org/10.1055/a-2438-0670
Semler, S.C., Boeker, M., Eils, R., Krefting, D., Loeffler, M., Bussmann, J.,... Prokosch, H.-U. (2024). Die Medizininformatik-Initiative im Überblick – Aufbau einer Gesundheitsforschungsdateninfrastruktur in Deutschland. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, 67(6), 616-628. https://doi.org/10.1007/s00103-024-03887-5
Zeiler, M., Dietzel, N., Kolominsky-Rabas, P., Grässel, E., & Prokosch, H.-U. (2024). Evaluation of a Digital Dementia Registry's IT Architecture After a Three-Year Period in Practice: digiDEM Bayern. Studies in Health Technology and Informatics, 313, 43-48. https://doi.org/10.3233/SHTI240010

2023

Ammer, T., Schützenmeister, A., Prokosch, H.-U., Rauh, M., Rank, C.M., & Zierk, J. (2023). A pipeline for the fully automated estimation of continuous reference intervals using real-world data. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-40561-3
Iancu, A., Leb, I., Prokosch, H.-U., & Rödle, W. (2023). Machine learning in medication prescription: A systematic review. International Journal of Medical Informatics, 180. https://doi.org/10.1016/j.ijmedinf.2023.105241
Keefer, A., Steichele, K., Grässel, E., Prokosch, H.-U., & Kolominsky-Rabas, P. (2023). Does Voluntary Work Contribute to Cognitive Performance? – An International Systematic Review. Journal of Multidisciplinary Healthcare, 16, 1097-1109. https://doi.org/10.2147/JMDH.S404880
Mang, J., Prokosch, H.-U., & Kapsner, L. (2023). Reproducibility in 2023 - An End-to-End Template for Analysis and Manuscript Writing. Studies in Health Technology and Informatics, 302, 58-62. https://doi.org/10.3233/SHTI230064
Prokosch, H.-U., Gebhardt, M., Gründner, J., Kleinert, P., Buckow, K., Rosenau, L., & Semler, S.C. (2023). Towards a National Portal for Medical Research Data (FDPG): Vision, Status, and Lessons Learned. In Maria Hägglund, Madeleine Blusi, Stefano Bonacina, Lina Nilsson, Inge Cort Madsen, Sylvia Pelayo, Anne Moen, Arriel Benis, Lars Lindsköld, Parisis Gallos (Eds.), Caring is Sharing – Exploiting the Value in Data for Health and Innovation. (pp. 307-311). IOS Press.
Reimer, K.C., Nadal, J., Meiselbach, H., Schmid, M., Schultheiss, U.T., Kotsis, F.,... Gronwald, W. (2023). Association of mineral and bone biomarkers with adverse cardiovascular outcomes and mortality in the German Chronic Kidney Disease (GCKD) cohort. Bone Research, 11(1). https://doi.org/10.1038/s41413-023-00291-8
Schüttler, C., Zerlik, M., Gründner, J., Köhler, T., Rosenau, L., Prokosch, H.-U., & Sedlmayr, B. (2023). Empowering Researchers to Query Medical Data and Biospecimens by Ensuring Appropriate Usability of a Feasibility Tool: Evaluation Study. JMIR Human Factors, 10. https://doi.org/10.2196/43782
Ziegler, J., Gründner, J., Rosenau, L., Erpenbeck, M., Prokosch, H.-U., & Deppenwiese, N. (2023). Towards a Bavarian Oncology Real World Data Research Platform. In Rainer Röhrig, Niels Grabe, Martin Haag, Ursula Hübner, Ulrich Sax, Carsten Oliver Schmidt, Martin Sedlmayr, Antonia Zapf (Eds.), German Medical Data Sciences 2023 – Science. Close to People. (pp. 78-85). IOS Press.

2022

Ammer, T., Schuetzenmeister, A., Prokosch, H.-U., Zierk, J., Rank, C.M., & Rauh, M. (2022). RIbench: A Proposed Benchmark for the Standardized Evaluation of Indirect Methods for Reference Interval Estimation. Clinical Chemistry. https://doi.org/10.1093/clinchem/hvac142
Ammer, T., Schutzenmeister, A., Prokosch, H.-U., Rauh, M., Zierk, J., & Rank, C.M. (2022). Enhancing refiner - Improving performance of reference interval estimation for skewed distributions. In CLINICA CHIMICA ACTA (pp. S294-S294). AMSTERDAM: ELSEVIER.
Bialke, M., Geidel, L., Hampf, C., Blumentritt, A., Penndorf, P., Schuldt, R.,... Hoffmann, W. (2022). A FHIR has been lit on gICS: facilitating the standardised exchange of informed consent in a large network of university medicine. BMC Medical Informatics and Decision Making, 22(1). https://doi.org/10.1186/s12911-022-02081-4
Fitzer, K., Haeuslschmid, R., Blasini, R., Altun, F.B., Hampf, C., Freiesleben, S.,... Gulden, C. (2022). Patient Recruitment System for Clinical Trials: Mixed Methods Study About Requirements at Ten University Hospitals. JMIR Medical Informatics, 10(4). https://doi.org/10.2196/28696
Gründner, J., Deppenwiese, N., Folz, M., Koehler, T., Kroll, B., Prokosch, H.-U.,... Majeed, R.W. (2022). The Architecture of a Feasibility Query Portal for Distributed COVID-19 Fast Healthcare Interoperability Resources (FHIR) Patient Data Repositories: Design and Implementation Study. JMIR Medical Informatics, 10(5). https://doi.org/10.2196/36709
Holweg, F., Achenbach, S., Deppenwiese, N., Gaede, L., & Prokosch, H.-U. (2022). Towards a FHIR-Based Data Model for Coronary Angiography Observations. In Thomas Bürkle, Kerstin Denecke, Jürgen Holm, Murat Sariyar, Michael Lehmann (Eds.), Healthcare of the Future 2022. (pp. 96-99). IOS Press.
Holzner, D., Apfelbacher, T., Rödle, W., Schüttler, C., Prokosch, H.-U., Mikolajczyk, R.,... Christoph, J. (2022). Attitudes and Acceptance Towards Artificial Intelligence in Medical Care. Studies in Health Technology and Informatics, 294, 68-72. https://doi.org/10.3233/SHTI220398
Kapsner, L., Brunner, T., Christiansen, H., Kisser, U., Mansoorian, S., Prokosch, H.-U.,... Medenwald, D. (2022). Postponements in Use of Radiotherapy during the first Wave of the COVID-19 Pandemic? An Analysis of Hospital Data. In STRAHLENTHERAPIE UND ONKOLOGIE (pp. S43-S43). HEIDELBERG: SPRINGER HEIDELBERG.
Leb, I., Magnin, S., Boeker, M., Prokosch, H.-U., Ammenwerth, E., & Glöggler, M. (2022). Classification of Patient Portals Described in Evaluation Studies Using the TOPCOP Taxonomy. In Thomas Bürkle, Kerstin Denecke, Jürgen Holm, Murat Sariyar, Michael Lehmann (Eds.), Healthcare of the Future 2022. (pp. 28-33).
Medenwald, D., Brunner, T., Christiansen, H., Kisser, U., Mansoorian, S., Vordermark, D.,... Kapsner, L. (2022). Shift of radiotherapy use during the first wave of the COVID-19 pandemic? An analysis of German inpatient data. Strahlentherapie und Onkologie. https://doi.org/10.1007/s00066-021-01883-1
Prokosch, H.-U., Baber, R., Bollmann, P., Gebhardt, M., Gründner, J., & Hummel, M. (2022). Aligning Biobanks and Data Integration Centers Efficiently (ABIDE_MI). In Thomas Bürkle, Kerstin Denecke, Jürgen Holm, Murat Sariyar, Michael Lehmann (Eds.), Healthcare of the Future 2022. (pp. 37-42). IOS Press.
Prokosch, H.-U., Bahls, T., Bialke, M., Eils, J., Fegeler, C., Gründner, J.,... Eils, R. (2022). The COVID-19 Data Exchange Platform of the German University Medicine. In Brigitte Séroussi, Patrick Weber, Ferdinand Dhombres, Cyril Grouin, Jan-David Liebe, Sylvia Pelayo, Andrea Pinna, Bastien Rance, Lucia Sacchi, Adrien Ugon, Arriel Benis, Parisis Gallos (Eds.), Challenges of Trustable AI and Added-Value on Health. (pp. 674-678). IOS Press.
Raupach, T., Held, J., Prokosch, H.-U., Rascher, W., & Zierk, J. (2022). Corrigendum to: “Resistance to antibacterial therapy in pediatric febrile urinary tract infectionsda single-center analysis” [J Pediatr Urol 16 (2020) 71–79] (Journal of Pediatric Urology (2020) 16(1) (71–79), (S1477513119303389), (10.1016/j.jpurol.2019.10.018)). Journal of Pediatric Urology, 18(1), 107-. https://doi.org/10.1016/j.jpurol.2021.11.021
Rosenau, L., Majeed, R.W., Ingenerf, J., Kiel, A., Kroll, B., Köhler, T.,... Gründner, J. (2022). Generation of a Fast Healthcare Interoperability Resources (FHIR)-based Ontology for Federated Feasibility Queries in the Context of COVID-19: Feasibility Study. JMIR Medical Informatics, 10(4). https://doi.org/10.2196/35789
Scheible, R., Caliskan, D., Fischer, P., Thomczyk, F., Zabka, S., Schneider, H.,... Gulden, C. (2022). AHD2FHIR: A Tool for Mapping of Natural Language Annotations to Fast Healthcare Interoperability Resources - A Technical Case Report. Studies in Health Technology and Informatics, 290, 32-36. https://doi.org/10.3233/SHTI220026
Schoenthaler, M., Fichtner, U.A., Boeker, M., Zoeller, D., Binder, H., Prokosch, H.-U.,... Farin-Glattacker, E. (2022). A nationwide registry for recurrent urolithiasis in the upper urinary tract - The RECUR study protocol. BMC Health Services Research, 22(1). https://doi.org/10.1186/s12913-022-08375-7
Schüttler, C., Jahns, R., Prokosch, H.-U., Wach, S., & Wullich, B. (2022). Biobanks, translational research and medical informatics. Die Urologie, 61(7), 722-727. https://doi.org/10.1007/s00120-022-01850-3
Sedlmayr, B., Sedlmayr, M., Kroll, B., Prokosch, H.-U., Gründner, J., & Schüttler, C. (2022). Improving COVID-19 Research of University Hospitals in Germany: Formative Usability Evaluation of the CODEX Feasibility Portal. Applied Clinical Informatics, 13(02), 400-409. https://doi.org/10.1055/s-0042-1744549
Steichele, K., Keefer, A., Dietzel, N., Grässel, E., Prokosch, H.-U., & Kolominsky-Rabas, P. (2022). The effects of exercise programs on cognition, activities of daily living, and neuropsychiatric symptoms in community-dwelling people with dementia-a systematic review. Alzheimer's Research and Therapy, 14(1). https://doi.org/10.1186/s13195-022-01040-5
Vass, A., Reinecke, I., Boeker, M., Prokosch, H.-U., & Gulden, C. (2022). Availability of Structured Data Elements in Electronic Health Records for Supporting Patient Recruitment in Clinical Trials. Studies in Health Technology and Informatics, 290, 130-134. https://doi.org/10.3233/SHTI220046

2021

Ammer, T., Schuetzenmeister, A., Prokosch, H.-U., Rauh, M., Rank, C.M., & Zierk, J. (2021). refineR: A Novel Algorithm for Reference Interval Estimation from Real-World Data. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-95301-2
Amr, A., Hinderer, M., Griebel, L., Deuber, D., Egger, C., Sedaghat-Hamedani, F.,... Meder, B. (2021). Controlling my genome with my smartphone: first clinical experiences of the PROMISE system. Clinical Research in Cardiology. https://doi.org/10.1007/s00392-021-01942-8
Caliskan, D., Zierk, J., Kraska, D., Schulz, S., Daumke, P., Prokosch, H.-U., & Kapsner, L. (2021). First Steps to Evaluate an NLP Tool's Medication Extraction Accuracy from Discharge Letters. In Rainer Röhrig, Tim Beißbarth, Werner Brannath, Hans-Ulrich Prokosch, Irene Schmidtmann, Susanne Stolpe, Antonia Zapf (Eds.), German Medical Data Sciences: Bringing Data to Life. (pp. 224-230). IOS Press.
Dietzel, N., Kürten, L., Karrer, L., Reichold, M., Köhler, L., Nagel, A.,... Kolominsky-Rabas, P. (2021). Digital Dementia Registry Bavaria - DigiDEM Bayern: Study protocol for a multicentre, prospective, longitudinal register study. BMJ Open, 11(2). https://doi.org/10.1136/bmjopen-2020-043473
Gründner, J., Gulden, C., Kampf, M., Mate, S., Prokosch, H.-U., & Zierk, J. (2021). A framework for criteria-based selection and processing of fast healthcare interoperability resources (FHIR) data for statistical analysis: Design and implementation study. JMIR Medical Informatics, 9(4). https://doi.org/10.2196/25645
Gulden, C., Blasini, R., Nassirian, A., Stein, A., Altun, F.B., Kirchner, M.,... Boeker, M. (2021). Prototypical clinical trial registry based on fast healthcare interoperability resources (FHIR): Design and implementation study. JMIR Medical Informatics, 9(1). https://doi.org/10.2196/20470
Kapsner, L., Kampf, M., Seuchter, S.A., Gründner, J., Gulden, C., Mate, S.,... Prokosch, H.-U. (2021). Reduced Rate of Inpatient Hospital Admissions in 18 German University Hospitals During the COVID-19 Lockdown. Frontiers in Public Health, 8. https://doi.org/10.3389/fpubh.2020.594117
Kapsner, L., Mang, J.M., Mate, S., Seuchter, S.A., Vengadeswaran, A., Bathelt, F.,... Prokosch, H.-U. (2021). Linking a Consortium-Wide Data Quality Assessment Tool with the MIRACUM Metadata Repository. Applied Clinical Informatics, 12(04), 826-835. https://doi.org/10.1055/s-0041-1733847
Kapsner, L., Zavgorodnij, M.G., Majorova, S.P., Hotz-Wagenblatt, A., Kolychev, O.V., Lebedev, I.N.,... Moskalev, E. (2021). BiasCorrector: Fast and accurate correction of all types of experimental biases in quantitative DNA methylation data derived by different technologies. International Journal of Cancer. https://doi.org/10.1002/ijc.33681
Le, T.T., Gutierrez-Sacristan, A., Son, J., Hong, C., South, A.M., Beaulieu-Jones, B.K.,... Xia, Z. (2021). Multinational characterization of neurological phenotypes in patients hospitalized with COVID-19. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-99481-9
Leb, I., Magnin, S., Prokosch, H.-U., & Boeker, M. (2021). Patient portals: Objectives, acceptance, and effects on health outcome - A scoping review of reviews. In Rainer Rohrig, Tim Beissbarth, Jochem Konig, Claudia Ose, Geraldine Rauch, Ulrich Sax, Bjorn Schreiweis, Martin Sedlmayr (Eds.), Studies in Health Technology and Informatics (pp. 194-201). Online, DE: IOS Press BV.
Maier, C., Kapsner, L., Mate, S., Prokosch, H.-U., & Kraus, S. (2021). Patient Cohort Identification on Time Series Data Using the OMOP Common Data Model. Applied Clinical Informatics, 12(1), 57-64. https://doi.org/10.1055/s-0040-1721481
Mate, S., Seuchter, S.A., Ehrenberg, K., Deppenwiese, N., Zierk, J., Prokosch, H.-U.,... Kapsner, L. (2021). A Multi-User Terminology Mapping Toolbox. In Rainer Röhrig, Tim Beißbarth, Werner Brannath, Hans-Ulrich Prokosch, Irene Schmidtmann, Susanne Stolpe, Antonia Zapf (Eds.), German Medical Data Sciences: Bringing Data to Life. (pp. 217-223). IOS Press.
Melzer, G., Maiwald, T., Prokosch, H.-U., & Ganslandt, T. (2021). Leveraging Real-World Data for the Selection of Relevant Eligibility Criteria for the Implementation of Electronic Recruitment Support in Clinical Trials. Applied Clinical Informatics, 12(1), 17-26. https://doi.org/10.1055/s-0040-1721010
Neher, S., Kapsner, L., Prokosch, H.-U., & Toddenroth, D. (2021). Design of an interactive web application for teaching uncertainty interpretations of clinical tests. In Rainer Rohrig, Tim Beissbarth, Jochem Konig, Claudia Ose, Geraldine Rauch, Ulrich Sax, Bjorn Schreiweis, Martin Sedlmayr (Eds.), Studies in Health Technology and Informatics (pp. 156-162). Online, DE: IOS Press BV.
Reichold, M., Dietzel, N., Chmelirsch, C., Kolominsky-Rabas, P., Grässel, E., & Prokosch, H.-U. (2021). Designing and Implementing an IT Architecture for a Digital Multicenter Dementia Registry: DigiDEM Bayern. Applied Clinical Informatics, 12(3), 551-563. https://doi.org/10.1055/s-0041-1731286
Reichold, M., Heß, M., Kolominsky-Rabas, P., Grässel, E., & Prokosch, H.-U. (2021). Usability evaluation of an offline electronic data capture app in a prospective multicenter dementia registry (digidem bayern): Mixed method study. JMIR Formative Research, 5(11). https://doi.org/10.2196/31649
Reichold, M., Selau, M., Grässel, E., Kolominsky-Rabas, P., & Prokosch, H.-U. (2021). EHealth Interventions for Dementia Using WordPress Plugins as a Flexible Dissemination for Dementia Service Providers. In Dieter Hayn, Gunter Schreier, Martin Baumgartner (Eds.), Studies in Health Technology and Informatics (pp. 1-9). Virtual, Online, AUT: IOS Press BV.
Reimer, N., Unberath, P., Busch, H., Börries, M., Metzger, P., Ustjanzew, A.,... Christoph, J. (2021). Challenges and Experiences Extending the cBioPortal for Cancer Genomics to a Molecular Tumor Board Platform. Studies in Health Technology and Informatics, 287, 139-143. https://doi.org/10.3233/SHTI210833
Röhrig, R., Beißbarth, T., Brannath, W., Prokosch, H.-U., Schmidtmann, I., Stolpe, S., & Zapf, A. (Eds.) (2021). German medical data sciences: Bringing data to life: Proceedings of the joint annual meeting of the German association of medical informatics, biometry and epidemiology (GMDS e.V.) and the Central European Network - International Biometric Society (CEN-IBS) 2020 in Berlin, Germany. IOS Press.
Schaaf, J., Sedlmayr, M., Sedlmayr, B., Prokosch, H.-U., & Storf, H. (2021). Evaluation of a clinical decision support system for rare diseases: a qualitative study. BMC Medical Informatics and Decision Making, 21(1). https://doi.org/10.1186/s12911-021-01435-8
Schüttler, C., Prokosch, H.-U., Hummel, M., Lablans, M., Kroll, B., & Engels, C. (2021). The journey to establishing an IT-infrastructure within the German Biobank Alliance. PLoS ONE, 16(9 September). https://doi.org/10.1371/journal.pone.0257632
Schüttler, C., Prokosch, H.-U., Sedlmayr, M., & Sedlmayr, B. (2021). Erratum: Evaluation of three feasibility tools for identifying patient data and biospecimen availability: Comparative usability study (JMIR Medical Informatics (2021) 9:7 (e25531) DOI: 10.2196/25531). JMIR Medical Informatics, 9(10). https://doi.org/10.2196/33105
Schüttler, C., Prokosch, H.-U., Sedlmayr, M., & Sedlmayr, B. (2021). Evaluation of three feasibility tools for identifying patient data and biospecimen availability: Comparative usability study. JMIR Medical Informatics, 9(7). https://doi.org/10.2196/25531
Schüttler, J., Mang, J.M., Kapsner, L., Seuchter, S.A., Binder, H., Zöller, D.,... Prokosch, H.-U. (2021). Studies on COVID-19 lethality: Causes and dynamics at German University Hospitals Letalität von Patienten mit COVID-19: Untersuchungen zu Ursachen und Dynamik an deutschen Universitätsklinika. Anästhesiologie & Intensivmedizin, 62(6), 244-257. https://doi.org/10.19224/ai2021.244
Sedlmayr, M., Schaaf, J., Sedlmayr, M., Prokosch, H.-U., Tegtbauer, N., Kadioglu, D.,... Storf, H. (2021). Visualization of Similar Patients in a Clinical Decision Support System for Rare Diseases - A Focus Group Study. In Rainer Röhrig, Tim Beißbarth, Werner Brannath, Hans-Ulrich Prokosch, Irene Schmidtmann, Susanne Stolpe, Antonia Zapf (Eds.), German Medical Data Sciences: Bringing Data to Life. (pp. 49-57). IOS Press.
Walther, T., Farin, E., Boeker, M., Prokosch, H.-U., Binder, H., Praus, F.,... Schoenthaler, M. (2021). RECUR - Establishment of An Automated Digital Registry for Patients with Recurrent Stones in the Upper Urinary Tract. Gesundheitswesen, 83, S27-S32. https://doi.org/10.1055/a-1651-0311
Zahn, J., Wimmer, S., Rödle, W., Toni, I., Sedlmayr, B., Prokosch, H.-U.,... Neubert, A. (2021). Development and Evaluation of a Web-Based Paediatric Drug Information System for Germany. Pharmacy, 9(1). https://doi.org/10.3390/pharmacy9010008
Zierk, J., Baum, H., Bertram, A., Boeker, M., Buchwald, A., Cario, H.,... Rauh, M. (2021). High-resolution pediatric reference intervals for 15 biochemical analytes described using fractional polynomials. Clinical Chemistry and Laboratory Medicine. https://doi.org/10.1515/cclm-2020-1371

2020

Becker, L., Ganslandt, T., Prokosch, H.-U., & Newe, A. (2020). Applied Practice and Possible Leverage Points for Information Technology Support for Patient Screening in Clinical Trials: Qualitative Study. JMIR Medical Informatics, 8(6), 1 - 14. https://doi.org/10.2196/15749
Brat, G.A., Weber, G.M., Gehlenborg, N., Avillach, P., Palmer, N.P., Chiovato, L.,... Kohane, I.S. (2020). International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium. npj Digital Medicine, 3(1). https://doi.org/10.1038/s41746-020-00308-0
Fuchs, M., Kreutzer, F.P., Kapsner, L., Mitzka, S., Just, A., Perbellini, F.,... Kunz, M. (2020). Integrative bioinformatic analyses of global transcriptome data decipher novel molecular insights into cardiac anti-fibrotic therapies. International Journal of Molecular Sciences, 21(13), 1-11. https://doi.org/10.3390/ijms21134727
Griebel, L., Hinderer, M., Amr, A., Meder, B., Schweig, M., Deuber, D.,... Prokosch, H.-U. (2020). The Patient as Genomic Data Manager - Evaluation of the PROMISE App. In Louise B. Pape-Haugaard, Christian Lovis, Inge Cort Madsen, Patrick Weber, Per Hostrup Nielsen, Philip Scott (Eds.), Digital Personalized Health and Medicine. (pp. 1061-1065). Amsterdam, Berlin, Washington: IOS Press.
Gründner, J., Wolf, N., Tögel, L., Haller, F., Prokosch, H.-U., & Christoph, J. (2020). Integrating Genomics and Clinical Data for Statistical Analysis by Using GEnome MINIng (GEMINI) and Fast Healthcare Interoperability Resources (FHIR): System Design and Implementation. Journal of Medical Internet Research, 22(10). https://doi.org/10.2196/19879
Kraus, S., Toddenroth, D., Staudigel, M., Rödle, W., Unberath, P., Griebel, L.,... Mate, S. (2020). Mapping the Entire Record-An Alternative Approach to Data Access from Medical Logic Modules. Applied Clinical Informatics, 11(2), 342-349. https://doi.org/10.1055/s-0040-1709708
Neuhaus, C., Schild, S., Eismann, H., Baus, J., Happel, O., Heller, A.R.,... St. Pierre, M. (2020). Funktionalität und Bedienung von eGENA, der elektronischen Gedächtnis- und Entscheidungshilfe für Notfälle in der Anästhesiologie. Anästhesiologie & Intensivmedizin, 61(7-8), 340-351. https://doi.org/10.19224/ai2020.340
Ploner, N., & Prokosch, H.-U. (2020). Integrating a Secure and Generic Mobile App for Patient Reported Outcome Acquisition into an EHR Infrastructure Based on FHIR Resources. In Louise B. Pape-Haugaard, Christian Lovis, Inge Cort Madsen, Patrick Weber, Per Hostrup Nielsen, Philip Scott (Eds.), Digital Personalized Health and Medicine. (pp. 991-995). Amsterdam, Berlin, Washington: IOS Press.
Rau, H., Geidel, L., Bialke, M., Blumentritt, A., Langanke, M., Liedtke, W.,... Hoffmann, W. (2020). The generic Informed Consent Service gICS®: implementation and benefits of a modular consent software tool to master the challenge of electronic consent management in research. Journal of Translational Medicine, 18(1), 287-. https://doi.org/10.1186/s12967-020-02457-y
Reichold, M., Dietzel, N., Karrer, L., Grässel, E., Kolominsky-Rabas, P., & Prokosch, H.-U. (2020). Stakeholder perspectives on the key components of a digital service platform supporting dementia - Digidem Bayern. In Gunter Schreier, Dieter Hayn, Alphons Eggerth (Eds.), Studies in Health Technology and Informatics (pp. 224-231). IOS Press BV.
Rödle, W., Caliskan, D., Prokosch, H.-U., & Kraus, S. (2020). Evaluation of Different Learning Algorithms of Neural Networks for Drug Dosing Recommendations in Pediatrics. In Günter Schreier, Dieter Hayn, Alphons Eggerth (Eds.), dHealth 2020 – Biomedical Informatics for Health and Care. (pp. 271-276). IOS Press.
Schaaf, J., Prokosch, H.-U., Boeker, M., Schaefer, J., Vasseur, J., Storf, H., & Sedlmayr, M. (2020). Interviews with experts in rare diseases for the development of clinical decision support system software - a qualitative study. BMC Medical Informatics and Decision Making, 20(1), 230-. https://doi.org/10.1186/s12911-020-01254-3
Schaaf, J., Sedlmayr, M., Prokosch, H.-U., Ganslandt, T., Schade-Brittinger, C., von Wagner, M.,... Storf, H. (2020). The Status Quo of Rare Diseases Centres for the Development of a Clinical Decision Support System - A Cross-Sectional Study. In Günter Schreier, Dieter Hayn, Alphons Eggerth (Eds.), dHealth 2020 – Biomedical Informatics for Health and Care. (pp. 176-183).
Schild, S., Gründner, J., Gulden, C., Prokosch, H.-U., St. Pierre, M., & Sedlmayr, M. (2020). Data Model Requirements for a Digital Cognitive Aid for Anesthesia to Support Intraoperative Crisis Management. Applied Clinical Informatics, 11(1), 190-199. https://doi.org/10.1055/s-0040-1703015
Schüttler, C., Huth, V., von Jagwitz-Biegnitz, M., Lablans, M., Prokosch, H.-U., & Griebel, L. (2020). A Federated Online Search Tool for Biospecimens (Sample Locator): Usability Study. Journal of Medical Internet Research, 22(8), e17739-. https://doi.org/10.2196/17739
Unberath, P., Prokosch, H.-U., Gründner, J., Erpenbeck, M., Maier, C., & Christoph, J. (2020). EHR-Independent Predictive Decision Support Architecture Based on OMOP. Applied Clinical Informatics, 11(3), 399-404. https://doi.org/10.1055/s-0040-1710393
Zierk, J., Arzideh, F., Kapsner, L., Prokosch, H.-U., Metzler, M., & Rauh, M. (2020). Reference Interval Estimation from Mixed Distributions using Truncation Points and the Kolmogorov-Smirnov Distance (kosmic). Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-58749-2

Related Research Fields

Digital Health

Research topics

Current projects

INTERPOLAR: WP3 - Interventionelle Studie: Universitätsklinikum Erlangen

Recent publications

2025

2024

2023

2022

2021

2020

Related Research Fields

Contact: